Anti-DNase gamma antibody (ab203669)
Key features and details
- Rabbit polyclonal to DNase gamma
- Suitable for: IHC-P
- Reacts with: Mouse, Rat
- Isotype: IgG
Overview
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Product name
Anti-DNase gamma antibody
See all DNase gamma primary antibodies -
Description
Rabbit polyclonal to DNase gamma -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Rat -
Immunogen
Synthetic peptide within Human DNase gamma aa 150-250 conjugated to keyhole limpet haemocyanin. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: Q13609 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), 1% BSA, 48.98% TBS, 1X
Aqueous buffered solution -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab203669 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
1/100 - 1/500.
When using a fluorescent probe the recommended dilution is 1/50 – 1/200. |
Notes |
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IHC-P
1/100 - 1/500. When using a fluorescent probe the recommended dilution is 1/50 – 1/200. |
Target
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Function
Has DNA hydrolytic activity. Does not bind to actin. Cleaves chromatin DNA to nucleosomal units. -
Tissue specificity
Liver and spleen. -
Sequence similarities
Belongs to the DNase I family. -
Cellular localization
Nucleus. May first pass through the ER membrane before being imported in the nucleus. - Information by UniProt
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Database links
- Entrez Gene: 13421 Mouse
- Entrez Gene: 116687 Rat
- SwissProt: O55070 Mouse
- SwissProt: O89107 Rat
- Unigene: 272258 Mouse
- Unigene: 29996 Rat
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Alternative names
- Deoxyribonuclease gamma antibody
- Deoxyribonuclease I like 3 antibody
- Deoxyribonuclease I like III antibody
see all
Images
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Immunohistochemical analysis of formalin-fixed, paraffin-embedded Mouse liver tissue labeling DNase gamma with ab203669 at 1/200 dilution followed by Goat Anti-Rabbit IgG, Cy3 conjugated secondary antibody at 1/200 dilution.
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Immunohistochemical analysis of formalin-fixed, paraffin-embedded Mouse spleen tissue labeling DNase gamma with ab203669 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.
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Immunohistochemical analysis of formalin-fixed, paraffin-embedded Rat heart tissue labeling DNase gamma with ab203669 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab203669 has been referenced in 1 publication.
- Deng Z et al. DNASE1L3 as a Prognostic Biomarker Associated with Immune Cell Infiltration in Cancer. Onco Targets Ther 14:2003-2017 (2021). PubMed: 33776450