FITC Anti-CD64 antibody [10.1] (ab119828)
Key features and details
- FITC Mouse monoclonal [10.1] to CD64
- Suitable for: Flow Cyt
- Reacts with: Human, Non human primates
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Related conjugates and formulations
Overview
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Product name
FITC Anti-CD64 antibody [10.1]
See all CD64 primary antibodies -
Description
FITC Mouse monoclonal [10.1] to CD64 -
Host species
Mouse -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human, Non human primates -
Immunogen
Tissue, cells or virus corresponding to Human CD64. Rheumatoid synovial fluid cells and fibronectin purified human monocytes
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Positive control
- Human blood cells.
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General notes
The reagent is free of unconjugated FITC and adjusted for direct use.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 0.2% BSA, 99% PBS -
Concentration information loading...
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Purity
Size exclusion -
Clonality
Monoclonal -
Clone number
10.1 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab119828 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt |
Use 4µl for 106 cells.
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Notes |
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Flow Cyt
Use 4µl for 106 cells. ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Target
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Function
High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. -
Tissue specificity
Monocyte/macrophage specific. -
Sequence similarities
Belongs to the immunoglobulin superfamily. FCGR1 family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains. -
Post-translational
modificationsPhosphorylated on serine residues. -
Cellular localization
Cell membrane. Stabilized at the cell membrane through interaction with FCER1G. - Information by UniProt
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Database links
- Entrez Gene: 2209 Human
- Entrez Gene: 2210 Human
- Omim: 146760 Human
- Omim: 601502 Human
- Omim: 601503 Human
- SwissProt: A6NKC4 Human
- SwissProt: P12314 Human
- SwissProt: Q92637 Human
see all -
Alternative names
- CD 64 antibody
- CD64 antibody
- CD64 antigen antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab119828 has been referenced in 4 publications.
- Brichard B et al. Intracellular cytokine profile of cord and adult blood monocytes. Bone Marrow Transplant 27:1081-6 (2001). PubMed: 11438825
- Hashimoto S et al. Enhancement of macrophage colony-stimulating factor-induced growth and differentiation of human monocytes by interleukin-10. Blood 89:315-21 (1997). PubMed: 8978307
- Jayaram Y et al. The Fc receptor, FcRI, and other activation molecules on human mononuclear phagocytes after treatment with interferon-gamma. Clin Exp Immunol 75:414-20 (1989). PubMed: 2495203
- Dougherty GJ et al. The human mononuclear phagocyte high-affinity Fc receptor, FcRI, defined by a monoclonal antibody, 10.1. Eur J Immunol 17:1453-9 (1987). PubMed: 3500057