Anti-GDF15 antibody (ab106006)
Key features and details
- Rabbit polyclonal to GDF15
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-GDF15 antibody
See all GDF15 primary antibodies -
Description
Rabbit polyclonal to GDF15 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Rat, Chimpanzee, Macaque monkey
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Immunogen
Synthetic peptide corresponding to a region near the carboxy terminal end of Human GDF15 protein. A residue of cysteine was added to facilitate coupling to KLH.
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Positive control
- GDF15 purified from CHO cells
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General notes
Dilute only prior to immediate use.
Expiration date is one (1) year from date of opening product.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 0.88% Sodium chloride, 0.42% Potassium phosphate -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
ab106006 was affinity purified from monospecific antiserum. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab106006 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | (1) |
1/2000 - 1/10000. Predicted molecular weight: 34 kDa.
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| Notes |
|---|
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WB
1/2000 - 1/10000. Predicted molecular weight: 34 kDa. |
Target
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Tissue specificity
Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney. -
Sequence similarities
Belongs to the TGF-beta family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 468770 Chimpanzee
- Entrez Gene: 9518 Human
- Entrez Gene: 29455 Rat
- Omim: 605312 Human
- SwissProt: Q99988 Human
- SwissProt: Q9Z0J6 Rat
- Unigene: 616962 Human
- Unigene: 44228 Rat
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Alternative names
- GDF 15 antibody
- GDF-15 antibody
- Gdf15 antibody
see all
Images
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Western blot - Anti-GDF15 antibody (ab106006)All lanes : Anti-GDF15 antibody (ab106006) at 1/2000 dilution
Lane 1 : GDF15 purified from CHO cells
Lane 2 : GDF15 purified from CHO cells, with immunizing peptide
Performed under reducing conditions.
Predicted band size: 34 kDa
A 14 kDa band corresponding to a GDF15 monomer and a 28 kDa band corresponding to dimerized GDF15 are indicated by arrowheads.
Lane 1 shows GDF15 detection, whereas lane 2 shows reactivity is blocked when ab106006 is pre-incubated with the immunizing peptide prior to Western blotting.
Datasheets and documents
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Datasheet download
References (2)
ab106006 has been referenced in 2 publications.
- Straub IR et al. Multi-OMICS study of a CHCHD10 variant causing ALS demonstrates metabolic rewiring and activation of endoplasmic reticulum and mitochondrial unfolded protein responses. Hum Mol Genet 30:687-705 (2021). PubMed: 33749723
- Frasca A et al. MECP2 mutations affect ciliogenesis: a novel perspective for Rett syndrome and related disorders. EMBO Mol Med 12:e10270 (2020). PubMed: 32383329
