Recombinant Anti-GPR56 antibody [EPR23908-109] (ab259820)
![Flow Cytometry - Anti-GPR56 antibody [EPR23908-109] (ab259820)](https://www.abcam.com/ps/products/259/ab259820/Images/ab259820-1-anti-gpr56-antibody-epr23908109-flow-cytometry-human-peripheral-blood-mononuclear-cell.jpg "Flow Cytometry - Anti-GPR56 antibody [EPR23908-109] (ab259820)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR23908-109] to GPR56
- Suitable for: Flow Cyt
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-GPR56 antibody [EPR23908-109]
See all GPR56 primary antibodies -
Description
Rabbit monoclonal [EPR23908-109] to GPR56 -
Host species
Rabbit -
Tested applications
Suitable for: Flow Cytmore details
Unsuitable for: ICC/IF,IHC-P,IP or WB -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- Flow cyt: Human peripheral blood mononuclear cells.
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General notes
This antibody ab259820 [EPR23908-109] is a different clone to ab274419 [EPR23908-115].
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR23908-109 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab259820 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt |
1/50.
|
| Notes |
|---|
|
Flow Cyt
1/50. |
Target
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Function
Could be involved in cell-cell interactions. -
Tissue specificity
Widely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells. -
Involvement in disease
Polymicrogyria, bilateral frontoparietal (BFPP) [MIM:606854]: A malformation of the cortex in which the brain surface is irregular and characterized by an excessive number of small gyri with abnormal lamination, most severe in the frontoparietal regions. BFPP clinical manifestations include developmental and psychomotor delay, cerebellar and pyramidal signs, truncal ataxia, seizures, hyperreflexia. Polymicrogyria is a heterogeneous disorder, considered to be the result of postmigratory abnormal cortical organization. Note=The disease is caused by mutations affecting the gene represented in this entry. -
Sequence similarities
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 1 GPS domain. -
Post-translational
modificationsThe endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 9289 Human
- Omim: 604110 Human
- SwissProt: Q9Y653 Human
- Unigene: 513633 Human
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Alternative names
- 7 transmembrane protein with no EGF like N terminal domains 1 antibody
- BFPP antibody
- DKFZp781L1398 antibody
see all
Images
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Flow Cytometry - Anti-GPR56 antibody [EPR23908-109] (ab259820)
Flow cytometric analysis of Human peripheral blood mononuclear cell (PBMC) cells labelling GPR56 with ab259820 at 1/50 dilution (1ug) (Right) compared with a Rabbit monoclonal IgG (ab172730) isotype control (Left). Goat anti rabbit IgG (Alexa Fluor® 488, ab150077) at 1/2000 dilution was used as the secondary antibody.
Cells were stained with rabbit IgG or ab259820. Then stained with anti-CD56 conjugated to BV421.
Gated on viable cells.
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![Anti-GPR56 antibody [EPR23908-109] (ab259820)](https://www.abcam.com/ps/products/259/ab259820/Images/ab259820-2-benefits-of-recombinant-antibodies.png)
Anti-GPR56 antibody [EPR23908-109] (ab259820)
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
Certificate of Compliance
References (0)
ab259820 has not yet been referenced specifically in any publications.