Anti-HLA class I A, B, C antibody (ab126237)
Key features and details
- Rabbit polyclonal to HLA class I A, B, C
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-HLA class I A, B, C antibody -
Description
Rabbit polyclonal to HLA class I A, B, C -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 206 of Human HLA class I A, B, C (AAH03069).
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Positive control
- A549 whole cell lysate; HepG2 whole cell lysate (ab7900)
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab126237 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 41 kDa.
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| Notes |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 41 kDa. |
Target
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Function
Involved in the presentation of foreign antigens to the immune system. -
Sequence similarities
Belongs to the MHC class I family.
Contains 1 Ig-like C1-type (immunoglobulin-like) domain. -
Post-translational
modificationsPolyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 3105 Human
- Entrez Gene: 3106 Human
- Entrez Gene: 3107 Human
- Omim: 142800 Human
- Omim: 142830 Human
- Omim: 142840 Human
- SwissProt: P01889 Human
- SwissProt: P04222 Human
see all -
Alternative names
- 1A03_HUMAN antibody
- A-1 alpha chain antibody
- A-3 alpha chain antibody
see all
Images
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Western blot - Anti-HLA class I A, B, C antibody (ab126237)Anti-HLA class I A, B, C antibody (ab126237) at 1/1000 dilution + A549 whole cell lysate at 30 µg
Predicted band size: 41 kDa
10% SDS PAGE
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab126237 has not yet been referenced specifically in any publications.