Recombinant HRP Anti-Extracellular matrix protein 1 antibody [EPR6701] (ab306228)
![HRP Anti-Extracellular matrix protein 1 antibody [EPR6701] (ab306228)](https://www.abcam.com/ps/products/306/ab306228/Images/ab306228-1-mto-conjugates-benefits-of-recombinant-antibodies.jpg "HRP Anti-Extracellular matrix protein 1 antibody [EPR6701] (ab306228)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- HRP Rabbit monoclonal [EPR6701] to Extracellular matrix protein 1
- Suitable for: Target binding affinity, Antibody labelling
- Conjugation: HRP
Related conjugates and formulations
Overview
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Product name
HRP Anti-Extracellular matrix protein 1 antibody [EPR6701]
See all Extracellular matrix protein 1 primary antibodies -
Description
HRP Rabbit monoclonal [EPR6701] to Extracellular matrix protein 1 -
Host species
Rabbit -
Conjugation
HRP -
Tested applications
Suitable for: Target binding affinity, Antibody labellingmore details -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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General notes
This conjugated primary antibody is manufactured using Abcam's Lightning-Link® technology. It is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone. This conjugated antibody is eligible for Abtrial: learn more here.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. Store In the Dark. -
Storage buffer
pH: 7.40
Preservative: 0.1% Proclin 300 Solution
Constituents: 30% Glycerol (glycerin, glycerine), 1% BSA, 68% PBS -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR6701 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab306228 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Target binding affinity |
Use at an assay dependent concentration.
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| Antibody labelling |
Use at an assay dependent concentration.
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| Notes |
|---|
|
Target binding affinity
Use at an assay dependent concentration. |
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Antibody labelling
Use at an assay dependent concentration. |
Target
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Function
Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. -
Tissue specificity
Expressed in breast cancer tissues. Little or no expression observed in normal breast tissues. Expressed in skin; wide expression is observed throughout the dermis with minimal expression in the epidermis. -
Involvement in disease
Defects in ECM1 are the cause of lipoid proteinosis (LiP) [MIM:247100]; also known as lipoid proteinosis of Urbach and Wiethe or hyalinosis cutis et mucosae. LiP is a rare autosomal recessive disorder characterized by generalized thickening of skin, mucosae and certain viscera. Classical features include beaded eyelid papules and laryngeal infiltration leading to hoarseness. Histologically, there is widespread deposition of hyaline material and disruption/reduplication of basement membrane. -
Cellular localization
Secreted > extracellular space > extracellular matrix. - Information by UniProt
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Alternative names
- ECM 1 antibody
- Ecm1 antibody
- ECM1_HUMAN antibody
see all
Images
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HRP Anti-Extracellular matrix protein 1 antibody [EPR6701] (ab306228)
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab306228 has not yet been referenced specifically in any publications.