Anti-HSD17B4 antibody [8E5AB11] (ab110297)
![Immunoprecipitation - Anti-HSD17B4 antibody [8E5AB11] (ab110297)](https://www.abcam.com/ps/products/110/ab110297/Images/ab110297-123538-anti-hsd17b4-antibody-8e5ab11-immunoprecipitation.jpg "Immunoprecipitation - Anti-HSD17B4 antibody [8E5AB11] (ab110297)")
Key features and details
- Mouse monoclonal [8E5AB11] to HSD17B4
- Suitable for: IP
- Reacts with: Human
- Isotype: IgG3
Overview
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Product name
Anti-HSD17B4 antibody [8E5AB11]
See all HSD17B4 primary antibodies -
Description
Mouse monoclonal [8E5AB11] to HSD17B4 -
Host species
Mouse -
Tested applications
Suitable for: IPmore details -
Species reactivity
Reacts with: Human -
Immunogen
The details of the immunogen for this antibody are not available.
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Positive control
- Human Liver Microsomes.
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General notes
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Product was previously marketed under the MitoSciences sub-brand.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Do Not Freeze. -
Storage buffer
pH: 7.5
Preservative: 0.02% Sodium azide
Constituent: HEPES buffered saline -
Concentration information loading... -
Purity
Ammonium Sulphate Precipitation -
Purification notes
ab110297 is produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation. -
Clonality
Monoclonal -
Clone number
8E5AB11 -
Isotype
IgG3 -
Light chain type
kappa -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab110297 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IP |
Use at an assay dependent dilution.
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| Notes |
|---|
|
IP
Use at an assay dependent dilution. |
Target
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Function
Bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids. Catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. -
Tissue specificity
Present in many tissues with highest concentrations in liver, heart, prostate and testis. -
Pathway
Lipid metabolism; fatty acid beta-oxidation. -
Involvement in disease
D-bifunctional protein deficiency
Perrault syndrome 1 -
Sequence similarities
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Contains 1 MaoC-like domain.
Contains 1 SCP2 domain. -
Cellular localization
Peroxisome. - Information by UniProt
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Database links
- Entrez Gene: 3295 Human
- Omim: 601860 Human
- SwissProt: P51659 Human
- Unigene: 406861 Human
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Alternative names
- 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase antibody
- 17 beta HSD 4 antibody
- 17 beta HSD IV antibody
see all
Images
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Immunoprecipitation - Anti-HSD17B4 antibody [8E5AB11] (ab110297)Immunoprecipitation with ab110297 from Human Liver Microsomes.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab110297 has been referenced in 1 publication.
- Jo DS et al. Loss of HSPA9 induces peroxisomal degradation by increasing pexophagy. Autophagy 16:1989-2003 (2020). PubMed: 31964216