Anti-Human Serum Albumin antibody (ab19179)
Key features and details
- Goat polyclonal to Human Serum Albumin
- Suitable for: Immunoelectrophoresis, Double Immunodiffusion
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Human Serum Albumin antibody
See all Human Serum Albumin primary antibodies -
Description
Goat polyclonal to Human Serum Albumin -
Host species
Goat -
Specificity
By immunoelectrophoresis, the antiserum reacts specifically with human albumin. No antibody was detected against other serum proteins. -
Tested applications
Suitable for: Immunoelectrophoresis, Double Immunodiffusionmore details -
Species reactivity
Reacts with: Human -
Immunogen
Full length protein corresponding to Human Human Serum Albumin. Serum albumin
Database link: P02768 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 6.8
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
IgG fraction -
Purification notes
The antiserum was fractionated and passed over DEAE to yield an IgG fraction. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab19179 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Immunoelectrophoresis | ||
| Double Immunodiffusion |
| Notes |
|---|
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Function
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. -
Tissue specificity
Plasma. -
Involvement in disease
Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. -
Sequence similarities
Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains. -
Post-translational
modificationsKenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 213 Human
- Omim: 103600 Human
- SwissProt: P02768 Human
- Unigene: 418167 Human
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Alternative names
- alb antibody
- ALBU_HUMAN antibody
- Albumin (32 AA) antibody
see all
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab19179 has not yet been referenced specifically in any publications.