Recombinant Anti-IL-2 Receptor alpha antibody [SP176], prediluted (ab150306)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [SP176] to IL-2 Receptor alpha, prediluted
- Suitable for: IHC-P, WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-IL-2 Receptor alpha antibody [SP176], prediluted
See all IL-2 Receptor alpha primary antibodies -
Description
Rabbit monoclonal [SP176] to IL-2 Receptor alpha, prediluted -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide within Human IL-2 Receptor alpha aa 250 to the C-terminus (C terminal). The exact sequence is proprietary.
Database link: P01589 -
Positive control
- MOLT4 cell lysate; Human tonsil tissue.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Do Not Freeze. -
Storage buffer
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: Tris buffered saline, 1% BSA -
Concentration information loading...
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Purity
Protein A/G purified -
Purification notes
Purified from TCS by protein A/G. -
Clonality
Monoclonal -
Clone number
SP176 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab150306 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
1/1. Boil tissue section in EDTA buffer, pH 8.0 for 10 min followed by cooling at room temperature for 20 min.
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WB |
1/1. Predicted molecular weight: 31 kDa.
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Notes |
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IHC-P
1/1. Boil tissue section in EDTA buffer, pH 8.0 for 10 min followed by cooling at room temperature for 20 min. |
WB
1/1. Predicted molecular weight: 31 kDa. |
Target
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Function
Receptor for interleukin-2. -
Involvement in disease
Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels. -
Sequence similarities
Contains 2 Sushi (CCP/SCR) domains. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 3559 Human
- Entrez Gene: 16184 Mouse
- Entrez Gene: 25704 Rat
- Omim: 147730 Human
- SwissProt: P01589 Human
- SwissProt: P01590 Mouse
- SwissProt: P26897 Rat
- Unigene: 231367 Human
see all -
Alternative names
- Interleukin 2 receptor alpha chain antibody
- CD25 antibody
- CD25 antigen antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-2 Receptor alpha antibody [SP176], prediluted (ab150306)Immunohistochemical analysis of formalin fixed, paraffin embedded Human tonsil tissue labelling IL2 Receptor alpha with ab150306.
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Anti-IL-2 Receptor alpha antibody [SP176], prediluted (ab150306) + MOLT4 cell lysate
Predicted band size: 31 kDa
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab150306 has not yet been referenced specifically in any publications.