Anti-Interferon alpha 1 antibody (ab191903)
Key features and details
- Rabbit polyclonal to Interferon alpha 1
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-Interferon alpha 1 antibody
See all Interferon alpha 1 primary antibodies -
Description
Rabbit polyclonal to Interferon alpha 1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide corresponding to Human Interferon alpha 1 aa 50-150.
Database link: P01562 -
Positive control
- WB: HEK-293T, NIH/3T3 and H9c2 whole cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
ab191903 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab191903 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
Use at an assay dependent concentration. Detects a band of approximately 24 kDa (predicted molecular weight: 22 kDa).
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| Notes |
|---|
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WB
Use at an assay dependent concentration. Detects a band of approximately 24 kDa (predicted molecular weight: 22 kDa). |
Target
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Function
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. -
Sequence similarities
Belongs to the alpha/beta interferon family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 3439 Human
- Entrez Gene: 3447 Human
- Entrez Gene: 15962 Mouse
- Entrez Gene: 230396 Mouse
- Entrez Gene: 298210 Rat
- Omim: 147660 Human
- SwissProt: P01562 Human
- SwissProt: P01572 Mouse
see all -
Alternative names
- IFL antibody
- IFN alpha antibody
- IFN alpha 1/13 antibody
see all
Images
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Western blot - Anti-Interferon alpha 1 antibody (ab191903)All lanes : Anti-Interferon alpha 1 antibody (ab191903)
Lane 1 : HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
Lane 2 : NIH/3T3 (Mouse embryo fibroblast cell line) whole cell lysate
Lane 3 : H9c2 (Rat heart myoblast cell line) whole cell lysate
Predicted band size: 22 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab191903 has been referenced in 2 publications.
- Huang B et al. MiR-103/miR-107 inhibits enterovirus 71 replication and facilitates type I interferon response by regulating SOCS3/STAT3 pathway. Biotechnol Lett 43:1357-1369 (2021). PubMed: 33796959
- Xiao W et al. Splenectomy delays fracture healing by affecting the level of tumor necrosis factor alpha, interleukin 6 and bone morphogenetic protein. Adv Clin Exp Med 27:165-171 (2018). PubMed: 29521058