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RecombinantRabMAb

Recombinant Anti-KIF3A antibody [EPR5087] (ab133587)

Submit a review Submit a question References (2)
Western blot - Anti-KIF3A antibody [EPR5087] (ab133587)
  • OI-RD Scanning - Anti-KIF3A antibody [EPR5087] (ab133587)
  • Anti-KIF3A antibody [EPR5087] (ab133587)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR5087] to KIF3A
  • Suitable for: WB
  • Reacts with: Human

Conjugates logo Related conjugates and formulations

Carrier Free

Overview

  • Product name

    Anti-KIF3A antibody [EPR5087]
    See all KIF3A primary antibodies

  • Description

    Rabbit monoclonal [EPR5087] to KIF3A

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF or IHC-P

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat

  • Immunogen

    Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.

  • Positive control

    • Fetal brain lysate, SH-SY5Y and 293T cell lysates

  • General notes

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

Properties

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab133587 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
1/1000 - 1/10000. Predicted molecular weight: 80 kDa.
Notes
WB
1/1000 - 1/10000. Predicted molecular weight: 80 kDa.
Application notes
Is unsuitable for Flow Cyt,ICC/IF or IHC-P.

Target

  • Function

    Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro.

  • Sequence similarities

    Belongs to the kinesin-like protein family. Kinesin II subfamily.
    Contains 1 kinesin-motor domain.

  • Cellular localization

    Cytoplasm > cytoskeleton.
  • Information by UniProt

  • Database links

    • Alternative names

      • KIF 3 antibody
      • KIF 3A antibody
      • KIF3 antibody
      • Kif3a antibody
      • KIF3A_HUMAN antibody
      • Kifl antibody
      • Kinesin family member 3A antibody
      • Kinesin family protein 3 antibody
      • Kinesin family protein 3A antibody
      • Kinesin like protein KIF 3A antibody
      • Kinesin like protein KIF3A antibody
      • Kinesin-like protein KIF3A antibody
      • Kns3 antibody
      • Microtubule plus end directed kinesin motor 3A antibody
      • Microtubule plus end-directed kinesin motor 3A antibody
      see all

    Images

    • Western blot - Anti-KIF3A antibody [EPR5087] (ab133587)
      Western blot - Anti-KIF3A antibody [EPR5087] (ab133587)
      All lanes : Anti-KIF3A antibody [EPR5087] (ab133587) at 1/1000 dilution

      Lane 1 : Fetal brain lysate
      Lane 2 : SH-SY5Y cell lysate
      Lane 3 : 293T cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled Goat anti-Rabbit IgG at 1/2000 dilution

      Predicted band size: 80 kDa

    • OI-RD Scanning - Anti-KIF3A antibody [EPR5087] (ab133587)
      OI-RD Scanning - Anti-KIF3A antibody [EPR5087] (ab133587)
      Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD
    • Anti-KIF3A antibody [EPR5087] (ab133587)
      Anti-KIF3A antibody [EPR5087] (ab133587)

    References (2)

    Publishing research using ab133587? Please let us know so that we can cite the reference in this datasheet.

    ab133587 has been referenced in 2 publications.

    • Xiong T  et al. MicroRNA-145-5p promotes asthma pathogenesis by inhibiting kinesin family member 3A expression in mouse airway epithelial cells. J Int Med Res 47:3307-3319 (2019). PubMed: 31264490
    • Jiang S  et al. Disruption of kif3a results in defective osteoblastic differentiation in dental mesenchymal stem/precursor cells via the Wnt signaling pathway. Mol Med Rep 14:1891-900 (2016). WB ; Human . PubMed: 27432616

    Customer reviews and Q&As

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