Anti-LRIG3 antibody (ab197989)
Key features and details
- Rabbit polyclonal to LRIG3
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-LRIG3 antibody -
Description
Rabbit polyclonal to LRIG3 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human LRIG3. (Near the C terminal; NP_700356).
Database link: Q6UXM1 -
Positive control
- Human esophagus cancer tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab197989 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
1/25 - 1/100.
|
| Notes |
|---|
|
IHC-P
1/25 - 1/100. |
Target
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Function
May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1. -
Tissue specificity
Widely expressed. -
Sequence similarities
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 15 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain. -
Cellular localization
Cell membrane. Cytoplasmic vesicle membrane. Detected in cytoplasmic vesicles when coexpressed with ERBB4. - Information by UniProt
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Database links
- Entrez Gene: 121227 Human
- Omim: 608870 Human
- SwissProt: Q6UXM1 Human
- Unigene: 253736 Human
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Alternative names
- Leucine-rich repeats and immunoglobulin-like domains protein 3 antibody
- Leucine-rich repeats- and immunoglobulin-like domains- containing protein 3 antibody
- LIG-3 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LRIG3 antibody (ab197989)
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue labeling LRIG3 with ab197989 at 1/50 dilution.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab197989 has been referenced in 1 publication.
- Cheng F et al. The Prognostic and Therapeutic Potential of LRIG3 and Soluble LRIG3 in Glioblastoma. Front Oncol 9:447 (2019). PubMed: 31245283