Recombinant Anti-NMBR antibody [EPR6880] (ab134141)
![Western blot - Anti-NMBR antibody [EPR6880] (ab134141)](https://www.abcam.com/ps/products/134/ab134141/Images/ab134141-148392-anti-nmbr-antibody-epr6880-western-blot.jpg "Western blot - Anti-NMBR antibody [EPR6880] (ab134141)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6880] to NMBR
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-NMBR antibody [EPR6880]
See all NMBR primary antibodies -
Description
Rabbit monoclonal [EPR6880] to NMBR -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF or IHC-P -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat
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Immunogen
Synthetic peptide within Human NMBR aa 1-100. The exact sequence is proprietary.
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Positive control
- A549, Caco2 and 293T cell lysates.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20ºC. -
Dissociation constant (KD)
KD = 2.15 x 10 -11 M Learn more about KD -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR6880 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab134141 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/10000 - 1/50000. Predicted molecular weight: 43 kDa.
|
| Notes |
|---|
|
WB
1/10000 - 1/50000. Predicted molecular weight: 43 kDa. |
Application notes
Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
Target
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Function
Receptor for neuromedin-B. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 4829 Human
- Entrez Gene: 18101 Mouse
- Entrez Gene: 25264 Rat
- Omim: 162341 Human
- SwissProt: P28336 Human
- SwissProt: O54799 Mouse
- SwissProt: P24053 Rat
- Unigene: 654478 Human
see all -
Alternative names
- Neuromedin B preferring bombesin receptor antibody
- Neuromedin B receptor antibody
- Neuromedin-B receptor antibody
see all
Images
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Western blot - Anti-NMBR antibody [EPR6880] (ab134141)All lanes : Anti-NMBR antibody [EPR6880] (ab134141) at 1/10000 dilution
Lane 1 : A549 cell lysate
Lane 2 : Caco2 cell lysate
Lane 3 : 293T cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat Anti-rabbit HRP at 1/2000 dilution
Predicted band size: 43 kDa -
![OI-RD Scanning - Anti-NMBR antibody [EPR6880] (ab134141)](https://www.abcam.com/ps/products/134/ab134141/Images/ab134141-148391-anti-nmbr-antibody-epr6880.jpg)
OI-RD Scanning - Anti-NMBR antibody [EPR6880] (ab134141) -
![Anti-NMBR antibody [EPR6880] (ab134141)](https://www.abcam.com/ps/products/134/ab134141/Images/ab134141-3-benefits-of-recombinant-antibodies.png)
Anti-NMBR antibody [EPR6880] (ab134141)
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab134141 has been referenced in 2 publications.
- Yang G et al. Role of neuromedin B and its receptor in the innate immune responses against influenza A virus infection in vitro and in vivo. Vet Res 50:80 (2019). PubMed: 31601264
- Meng L et al. Ultrasound-microbubbles-mediated microRNA-449a inhibits lung cancer cell growth via the regulation of Notch1. Onco Targets Ther 12:7437-7450 (2019). PubMed: 31686849