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RecombinantRabMAb

Recombinant PE Anti-AMPK alpha 1 antibody [Y365] (ab303053)

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PE Anti-AMPK alpha 1 antibody [Y365] (ab303053)

    Key features and details

    • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
    • PE Rabbit monoclonal [Y365] to AMPK alpha 1
    • Suitable for: Target binding affinity, Antibody labelling
    • Conjugation: PE. Ex: 488nm, Em: 575nm

    Conjugates logo Related conjugates and formulations

    APC HRP Unconjugated

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    Overview

    • Product name

      PE Anti-AMPK alpha 1 antibody [Y365]
      See all AMPK alpha 1 primary antibodies
    • Description

      PE Rabbit monoclonal [Y365] to AMPK alpha 1
    • Host species

      Rabbit
    • Conjugation

      PE. Ex: 488nm, Em: 575nm
    • Tested applications

      Suitable for: Target binding affinity, Antibody labellingmore details
    • Immunogen

      Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.

    • General notes

      This conjugated primary antibody is manufactured using Abcam's Lightning-Link® technology. It is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.

      For suitable applications and species reactivity, please refer to the unconjugated version of this clone. This conjugated antibody is eligible for Abtrial: learn more here.

      This product is a recombinant monoclonal antibody, which offers several advantages including:

      • - High batch-to-batch consistency and reproducibility
      • - Improved sensitivity and specificity
      • - Long-term security of supply
      • - Animal-free production
      For more information see here.

      Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at +4°C. Avoid freeze / thaw cycle. Store In the Dark.
    • Storage buffer

      pH: 7.4
      Preservative: 0.02% Sodium azide
      Constituents: 98% PBS, 1% BSA
    • Concentration information loading...
    • Purity

      Protein A purified
    • Clonality

      Monoclonal
    • Clone number

      Y365
    • Isotype

      IgG
    • Research areas

      • Neuroscience
      • Neurology process
      • Neurodegenerative disease
      • Alzheimer's disease
      • Amyloid
      • Signal Transduction
      • Protein Phosphorylation
      • Ser / Thr Kinases
      • Other Kinases
      • Cardiovascular
      • Lipids / Lipoproteins
      • Fatty Acids
      • Metabolism
      • Cancer
      • Cancer Metabolism
      • Metabolic signaling pathway
      • Integration of energy metabolism
      • Cancer
      • Cancer Metabolism
      • Response to hypoxia
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Lipid and lipoprotein metabolism
      • Fatty acids
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Energy transfer pathways
      • Integration of energy
      • Metabolism
      • Pathways and Processes
      • Metabolism processes
      • Hypoxia
      • Metabolism
      • Types of disease
      • Neurodegenerative disease
      • Metabolism
      • Pathways and Processes
      • Redox metabolism
      • Fatty acid oxidation

    Associated products

    • Alternative Versions

      • Anti-AMPK alpha 1 antibody [Y365] - BSA and Azide free (ab210714)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab303053 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Target binding affinity
    Use at an assay dependent concentration.
    Antibody labelling
    Use at an assay dependent concentration.
    Notes
    Target binding affinity
    Use at an assay dependent concentration.
    Antibody labelling
    Use at an assay dependent concentration.

    Target

    • Function

      Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
    • Sequence similarities

      Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
      Contains 1 protein kinase domain.
    • Target information above from: UniProt accession Q13131 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Alternative names

      • 5 AMP activated protein kinase alpha 1catalytic subunit antibody
      • 5 AMP activated protein kinase catalytic alpha 1 chain antibody
      • 5' AMP activated protein kinase catalytic subunit alpha 1 antibody
      • 5'-AMP-activated protein kinase catalytic subunit alpha-1 antibody
      • AAPK1 antibody
      • AAPK1_HUMAN antibody
      • ACACA kinase antibody
      • acetyl CoA carboxylase kinase antibody
      • AI194361 antibody
      • AI450832 antibody
      • AL024255 antibody
      • AMP -activate kinase alpha 1 subunit antibody
      • AMP-activate kinase alpha 1 subunit antibody
      • AMP-activated protein kinase, catalytic, alpha -1 antibody
      • AMPK 1 antibody
      • AMPK alpha 1 antibody
      • AMPK alpha 1 chain antibody
      • AMPK antibody
      • AMPK subunit alpha 1 antibody
      • AMPK subunit alpha-1 antibody
      • AMPK1 antibody
      • AMPKa1 antibody
      • AMPKalpha1 antibody
      • C130083N04Rik antibody
      • cb116 antibody
      • EC 2.7.11.1 antibody
      • HMG CoA reductase kinase antibody
      • HMGCR kinase antibody
      • hormone sensitive lipase kinase antibody
      • Hydroxymethylglutaryl CoA reductase kinase antibody
      • im:7154392 antibody
      • kinase AMPK alpha1 antibody
      • MGC33776 antibody
      • MGC57364 antibody
      • OTTHUMP00000161795 antibody
      • OTTHUMP00000161796 antibody
      • PRKAA 1 antibody
      • PRKAA1 antibody
      • Protein kinase AMP activated alpha 1 catalytic subunit antibody
      • SNF1-like protein AMPK antibody
      • SNF1A antibody
      • Tau protein kinase PRKAA1 antibody
      • wu:fa94c10 antibody
      see all

    Images

    • PE Anti-AMPK alpha 1 antibody [Y365] (ab303053)
      PE Anti-AMPK alpha 1 antibody [Y365] (ab303053)

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab303053? Please let us know so that we can cite the reference in this datasheet.

    ab303053 has not yet been referenced specifically in any publications.

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