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RecombinantRabMAb

Recombinant PE Anti-Ndufs4 antibody [EP7832] (ab306039)

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PE Anti-Ndufs4 antibody [EP7832] (ab306039)

    Key features and details

    • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
    • PE Rabbit monoclonal [EP7832] to Ndufs4
    • Suitable for: Target binding affinity, Antibody labelling
    • Conjugation: PE. Ex: 488nm, Em: 575nm

    Conjugates logo Related conjugates and formulations

    APC Carrier Free HRP Unconjugated

    Overview

    • Product name

      PE Anti-Ndufs4 antibody [EP7832]
      See all Ndufs4 primary antibodies
    • Description

      PE Rabbit monoclonal [EP7832] to Ndufs4
    • Host species

      Rabbit
    • Conjugation

      PE. Ex: 488nm, Em: 575nm
    • Tested applications

      Suitable for: Target binding affinity, Antibody labellingmore details
    • Immunogen

      Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.

    • General notes

      This conjugated primary antibody is manufactured using Abcam's Lightning-Link® technology. It is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.

      For suitable applications and species reactivity, please refer to the unconjugated version of this clone. This conjugated antibody is eligible for Abtrial: learn more here.

      This product is a recombinant monoclonal antibody, which offers several advantages including:

      • - High batch-to-batch consistency and reproducibility
      • - Improved sensitivity and specificity
      • - Long-term security of supply
      • - Animal-free production
      For more information see here.

      Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at +4°C. Store In the Dark.
    • Storage buffer

      pH: 7.40
      Preservative: 0.02% Sodium azide
      Constituents: 98% PBS, 1% BSA
    • Concentration information loading...
    • Purity

      Protein A purified
    • Clonality

      Monoclonal
    • Clone number

      EP7832
    • Isotype

      IgG
    • Research areas

      • Signal Transduction
      • Metabolism
      • Energy Metabolism
      • Signal Transduction
      • Metabolism
      • Mitochondrial
      • Neuroscience
      • Neurology process
      • Neurodegenerative disease
      • Other
      • Cancer
      • Cancer Metabolism
      • Metabolic signaling pathway
      • Integration of energy metabolism
      • Cancer
      • Cancer Metabolism
      • Cellular metabolic process
      • Metabolism
      • Pathways and Processes
      • Mitochondrial Metabolism
      • Mitochondrial markers
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Energy transfer pathways
      • Energy Metabolism
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Energy transfer pathways
      • Integration of energy
      • Metabolism
      • Pathways and Processes
      • Mitochondrial Metabolism
      • Oxidative phosphorylation
      • Complex I

    Associated products

    • Alternative Versions

      • Anti-Ndufs4 antibody [EP7832] - BSA and Azide free (ab232337)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab306039 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Target binding affinity
    Use at an assay dependent concentration.
    Antibody labelling
    Use at an assay dependent concentration.
    Notes
    Target binding affinity
    Use at an assay dependent concentration.
    Antibody labelling
    Use at an assay dependent concentration.

    Target

    • Function

      Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
    • Involvement in disease

      Defects in NDUFS4 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.
    • Sequence similarities

      Belongs to the complex I NDUFS4 subunit family.
    • Cellular localization

      Mitochondrion inner membrane.
    • Target information above from: UniProt accession O43181 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Alternative names

      • AQDQ antibody
      • CI 18 antibody
      • CI 18 kDa antibody
      • CI AQDQ antibody
      • CI-18 kDa antibody
      • CI-AQDQ antibody
      • Complex I 18 kDa antibody
      • Complex I AQDQ antibody
      • Complex I-18 kDa antibody
      • Complex I-AQDQ antibody
      • mitochondrial antibody
      • mitochondrial respiratory chain complex I (18 KD subunit) antibody
      • NADH coenzyme Q reductase antibody
      • NADH dehydrogenase (ubiquinone) Fe S protein 4 18kDa antibody
      • NADH dehydrogenase [ubiquinone] iron-sulfur protein 4 antibody
      • NADH dehydrogenase antibody
      • NADH ubiquinone oxidoreductase 18 kDa subunit antibody
      • NADH-ubiquinone oxidoreductase 18 kDa subunit antibody
      • NDUFS4 antibody
      • NDUS4_HUMAN antibody
      see all

    Images

    • PE Anti-Ndufs4 antibody [EP7832] (ab306039)
      PE Anti-Ndufs4 antibody [EP7832] (ab306039)

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab306039? Please let us know so that we can cite the reference in this datasheet.

    ab306039 has not yet been referenced specifically in any publications.

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