Recombinant Anti-Syndecan 3 antibody [EPR10648] (ab155952)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR10648] to Syndecan 3
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-Syndecan 3 antibody [EPR10648]
See all Syndecan 3 primary antibodies -
Description
Rabbit monoclonal [EPR10648] to Syndecan 3 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF or IHC-P -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- SH-SY5Y, Human spleen, Human adrenal gland and K562 lysates.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20ºC. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR10648 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab155952 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000 - 1/10000. Predicted molecular weight: 45 kDa.
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Notes |
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WB
1/1000 - 1/10000. Predicted molecular weight: 45 kDa. |
Target
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Function
Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. -
Tissue specificity
Expressed in the nervous system, the adrenal gland, and the spleen. -
Sequence similarities
Belongs to the syndecan proteoglycan family. -
Post-translational
modificationsO-glycosylated within the Thr/Ser-rich region which could interact with lectin domains on other molecules. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 9672 Human
- Entrez Gene: 20970 Mouse
- Entrez Gene: 116673 Rat
- Omim: 186357 Human
- SwissProt: O75056 Human
- SwissProt: Q64519 Mouse
- SwissProt: P33671 Rat
- Unigene: 158287 Human
see all -
Alternative names
- N-syndecan antibody
- Sdc3 antibody
- SDC3_HUMAN antibody
see all
Images
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All lanes : Anti-Syndecan 3 antibody [EPR10648] (ab155952) at 1/1000 dilution
Lane 1 : SH-SY5Y cell lysate
Lane 2 : Human spleen tissue lysate
Lane 3 : Human adrenal gland tissue lysate
Lane 4 : K562 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat anti-rabbit HRP at 1/2000 dilution
Predicted band size: 45 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab155952 has been referenced in 2 publications.
- Ding Y et al. LncRNA TRPM2-AS promotes ovarian cancer progression and cisplatin resistance by sponging miR-138-5p to release SDC3 mRNA. Aging (Albany NY) 13:6832-6848 (2021). PubMed: 33621194
- Liu S et al. Knockdown of pleiotrophin increases the risk of preeclampsia following vitrified-thawed embryo transfer. Int J Oncol 53:1847-1856 (2018). PubMed: 30226583