Anti-UCP4 antibody (ab183886)
Key features and details
- Rabbit polyclonal to UCP4
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-UCP4 antibody -
Description
Rabbit polyclonal to UCP4 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment within Human UCP4 aa 13-174. The exact sequence is proprietary.
Database link: O95847 -
Positive control
- SK-N-SH, IMR32 and SK-NAS whole cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab183886 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 36 kDa.
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| Notes |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 36 kDa. |
Target
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Function
UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. May play a role in thermoregulatory heat production and metabolism in brain. -
Tissue specificity
Found in adult and fetal brain. Present in most of the brain tissues, with low levels in spinal chord, corpus callosum and substantia nigra. -
Sequence similarities
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Contains 3 Solcar repeats. -
Cellular localization
Mitochondrion inner membrane. - Information by UniProt
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Database links
- Entrez Gene: 9481 Human
- SwissProt: O95847 Human
- Unigene: 40510 Human
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Alternative names
- Mitochondrial uncoupling protein 4 antibody
- SLC25A27 antibody
- Solute carrier family 25 member 27 antibody
see all
Images
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Western blot - Anti-UCP4 antibody (ab183886)All lanes : Anti-UCP4 antibody (ab183886) at 1/1000 dilution
Lane 1 : SK-N-SH whole cell lysate
Lane 2 : IMR32 whole cell lysate
Lane 3 : SK-N-AS whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 36 kDa12% SDS PAGE
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab183886 has not yet been referenced specifically in any publications.