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Anti-vGPCR antibody (ab25122)

Submit a review Q&A (1)

Key features and details

  • Rabbit polyclonal to vGPCR
  • Suitable for: Flow Cyt
  • Reacts with: Human herpesvirus 8
  • Isotype: IgG

Overview

  • Product name

    Anti-vGPCR antibody

  • Description

    Rabbit polyclonal to vGPCR

  • Host species

    Rabbit

  • Tested applications

    Suitable for: Flow Cytmore details

  • Species reactivity

    Reacts with: Human herpesvirus 8

  • Immunogen

    Recombinant fragment corresponding to vGPCR aa 1-41 (N terminal).

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.

  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituent: PBS
  • Concentration information loading...

  • Purity

    Protein A purified

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab25122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
Use at an assay dependent concentration.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

 
Notes
Flow Cyt
Use at an assay dependent concentration.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

 

Target

  • Relevance

    Kaposi's sarcoma-associated herpesvirus (KSHV, or human herpesvirus 8, HHV8), is a gamma herpesvirus that contain an open reading frame encoding a G protein-coupled receptor (GPCR) with putative 7 transmembrane domains. This GPCR has been shown to bind a number of chemokines including IL8, NAP2, PF4, MGSA/Gro alpha, I309, RANTES, MCP1, and MIP1 beta. The receptor is constitutively activated without chemokine binding, and it stimulates cell proliferation. KSHV GPCR is also a viral oncogene that stimulates angio-genesis through induction of VEGF expression. IP10, a chemokine, can inhibit constitutively activated KSHV GPCR.

  • Alternative names

    • Human Herpesvirus 8 GPCR antibody
    • Kaposi's sarcoma-associated herpesvirus GPCR antibody
    • KSHV GPCR antibody

References (0)

Publishing research using ab25122? Please let us know so that we can cite the reference in this datasheet.

ab25122 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Submit a review Submit a question

Question

Please provide list of antibodies to HHV8 virus

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Answer

Thank you for your telephone enquiry yesterday afternoon. As requested, here is a list of all our antibodies for detection of HHV8 virus. I can recommend to review the online datasheets for further information. ab4103 Rat monoclonal Anti-HHV8 antibody [LN35] Applications: IHC-Fr, IHC-P Click here (or use the following: https://www.abcam.com/HHV8-antibody-LN53-ab4103.html). ab12208 Rat monoclonal Anti-HHV8 Cyclin antibody [94B] Applications: IF, IP, WB Click here (or use the following: https://www.abcam.com/v-cyclin-antibody-94B-ab12208.html). ab25122 Rabbit polyclonal Anti-HHV8 GPCR antibody Applications: Flow Cyt Click here (or use the following: https://www.abcam.com/vGPCR-antibody-ab25122.html). ab16159 Sheep polyclonal Anti-HHV8 ORF62 antibody Applications: WB Click here (or use the following: https://www.abcam.com/HHV8-ORF62-antibody-ab16159.html). I hope this will be helpful to you. If you have any further questions, please do not hesitate to contact us.

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