Active human RP105 peptide (ab47675)
Key features and details
- Active: Yes
- Suitable for: WB, Blocking
Product nameActive human RP105 peptide
See all RP105 proteins and peptides
Biological activityThe peptide is used for blocking the activity of RP105 antibody (ab45430)
Our Abpromise guarantee covers the use of ab47675 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- CD180 antigen
FunctionMay cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells.
Tissue specificityExpressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells.
Sequence similaritiesBelongs to the Toll-like receptor family.
Contains 19 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Cellular localizationCell membrane.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
ab47675 has not yet been referenced specifically in any publications.