HIV gp41 L peptide (ab43148)
Key features and details
- Purity: > 95% HPLC
- Suitable for: WB, ELISA
Description
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Product name
HIV gp41 L peptide
See all HIV gp41 L proteins and peptides -
Biological activity
Immunoreactive with all sera of HIV type O infected individuals. -
Purity
> 95 % HPLC.
Peptide is >95% pure As determined by MASS Analysis. -
Animal free
No -
Nature
Synthetic
Specifications
Our Abpromise guarantee covers the use of ab43148 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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Form
Liquid -
Additional notes
Immunoreactive with all sera of HIV type O infected individuals.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Info
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Alternative names
- env
- Glycoprotein 41
- gp41
see all -
Relevance
The transmembrane protein gp41 (TM) acts as a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes. Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm. -
Cellular localization
Cell membrane
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab43148 has not yet been referenced specifically in any publications.
