HIV2 gp36 peptide (ab43147)
Key features and details
- Purity: > 95% HPLC
- Suitable for: ELISA, WB
Description
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Product name
HIV2 gp36 peptide
See all HIV2 gp36 proteins and peptides -
Biological activity
Immunoreactive with all sera of HIV-2 infected individuals. -
Purity
> 95 % HPLC.
Purity determined by HPLC-C18, and MASS Analysis. -
Animal free
No -
Nature
Synthetic
Specifications
Our Abpromise guarantee covers the use of ab43147 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
ELISA
Western blot
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Form
Liquid -
Additional notes
Immunoreactive with all sera of HIV-2 infected individuals.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Info
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Alternative names
- Gp36
- HIV 2
- Human immunodeficiency virus 2
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Relevance
HIV2 infections at present, are predominantly found in west Africa where it is the dominant form of HIV. Both HIV1 and HIV2 have the same modes of transmission and are associated with similar opportunistic infections and AIDS. In persons infected with HIV2, immunodeficiency seems to develop more slowly and to be milder, but as the disease advances, HIV2 infectiousness seems to increase. Little is known about the best approach to the clinical treatment and care of patients infected with HIV2. Some drugs used to treat HIV1 are ineffective. HIV1 and HIV2 have similar gag (viral core) and pol (polymerase) regions, they have relatively dissimilar env (envelope) regions. Owing to this lack of homology in the envelope region, there is little serologic cross-reactivity of the antibodies directed against the envelope antigens of both HIV1 and HIV2. The env gp36 ectodomain is highly conserved and elicits a type-specific antibody response. Hence, most licensed diagnostic assays incorporate gp36-derived antigens to detect HIV2 specific antibodies. It is becoming important to differentiate between single infection with either HIV1 or HIV2 and dual infection.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab43147 has not yet been referenced specifically in any publications.
