Recombinant Hepatitis B virus Hepatitis B Surface Antigen AD protein (ab193473)
Key features and details
- Expression system: Saccharomyces cerevisiae
- Purity: > 95% SDS-PAGE
- Suitable for: SDS-PAGE, ELISA, WB
Description
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Product name
Recombinant Hepatitis B virus Hepatitis B Surface Antigen AD protein -
Purity
> 95 % SDS-PAGE.
Recombinant Hepatitis B surface antigen AD expressed in Saccharomyces cerevisiae and purified via ionic exchange chromatography, size exclusion chromatography and sterile filtration. -
Expression system
Saccharomyces cerevisiae -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Hepatitis B virus -
Predicted molecular weight
24 kDa -
Additional sequence information
Surface antigen Ad.
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Specifications
Our Abpromise guarantee covers the use of ab193473 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
ELISA
Western blot
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C. Do Not Freeze.
Preservative: 0.09% Sodium azide
Constituent: 99% PBS
General Info
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Alternative names
- HBsAg
- Hep B surface antigen
- Hepatitis B Virus major surface antigen
see all -
Relevance
Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction. -
Cellular localization
Cell Membrane
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (1)
ab193473 has been referenced in 1 publication.
- Read BJ et al. Mannose-binding lectin and complement mediate follicular localization and enhanced immunogenicity of diverse protein nanoparticle immunogens. Cell Rep 38:110217 (2022). PubMed: 35021101
