Recombinant Human Cathepsin O protein (Tagged) (ab267932)
Key features and details
- Expression system: Mammalian
- Purity: > 85% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant Human Cathepsin O protein (Tagged)
See all Cathepsin O proteins and peptides -
Purity
> 85 % SDS-PAGE. -
Expression system
Mammalian -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
LPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSV QQVIDCSYNNYGCNGGSTLNALNWLNKMQVKLVKDSEYPFKAQNGLCHYF SGSHSGFSIKGYSAYDFSDQEDEMAKALLTFGPLVVIVDAVSWQDYLGGI IQHHCSSGEANHAVLITGFDKTGSTPYWIVRNSWGSSWGVDGYAHVKMGS NVCGIADSVSSIFV -
Predicted molecular weight
29 kDa including tags -
Amino acids
108 to 321 -
Tags
His tag N-Terminus -
Additional sequence information
Mature chain. N-terminal 10xHis-tagged and C-terminal Myc-tagged.
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab267932 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.2
Constituents: PBS, 6% Trehalose
General Info
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Alternative names
- Cathepsin O
- CATO_HUMAN
- Ctso
- CTSO1
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Function
Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover. -
Tissue specificity
Expressed in all tissues examined. High levels seen in the ovary, kidney and placenta while low levels seen in thymus and skeletal muscle. -
Sequence similarities
Belongs to the peptidase C1 family. -
Cellular localization
Lysosome. - Information by UniProt
Images
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SDS-PAGE - (ab267932)
SDS-PAGE analysis of ab267932 under reducing conditions.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (1)
ab267932 has been referenced in 1 publication.
- Mohan S et al. Processing of progranulin into granulins involves multiple lysosomal proteases and is affected in frontotemporal lobar degeneration. Mol Neurodegener 16:51 (2021). PubMed: 34344440
