Recombinant Human GATA3 protein (ab204202)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Suitable for: SDS-PAGE, Functional Studies
Description
-
Product name
Recombinant Human GATA3 protein -
Purity
> 90 % SDS-PAGE.
refolded and chromatographically purified. -
Expression system
Escherichia coli -
Accession
-
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
-
Species
Human -
Sequence
MASMTGGQQMGRGHHHHHHENLYFQGEVTADQPRWVSHHHPAVLNGQHPD THHPGLSHSYMDAA QYPLPEEVDVLFNIDGQGNHVPPYYGNSVRATVQ RYPPTHHGSQVCRPPLLHGSLPWLDGGKAL GSHHTASPWNLSPFSKTS IHHGSPGPLSVYPPASSSSLSGGHASPHLFTFPPTPPKDVSPDPSL ST PGSAGSARQDEKECLKYQVPLPDSMKLESSHSRGSMTALGGASSSTHHPI TTYPPYVPEYSS GLFPPSSLLGGSPTGFGCKSRPKARSSTGRECVNCG ATSTPLWRRDGTGHYLCNACGLYHKMNG QNRPLIKPKRRLSAARRAGT SCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKE GIQT RNRKMSSKSKKCKKVHDSLEDFPKNSSFNPAALSRHMSSLSHISPFSHSS HMLTTPTPMH PPSSLSFGPHHPSSMVTAMG -
Predicted molecular weight
51 kDa including tags -
Amino acids
2 to 443 -
Additional sequence information
Full length protein without initiator methionine and a small T7-His-TEV cleavage site Tag (29aa) fusion at its N-terminal
-
Associated products
-
Related Products
Specifications
Our Abpromise guarantee covers the use of ab204202 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
SDS-PAGE
Functional Studies
-
Form
Liquid -
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.32% Tris HCl, Sodium chloride, Potassium chloride, L-Arginine, EDTA, Glycerol
Also contains DTT.
General Info
-
Alternative names
- GATA 3
- GATA binding factor 3
- GATA binding protein 3
see all -
Function
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. -
Tissue specificity
T-cells and endothelial cells. -
Involvement in disease
Defects in GATA3 are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) [MIM:146255]; also known as Barakat syndrome. -
Sequence similarities
Contains 2 GATA-type zinc fingers. -
Cellular localization
Nucleus. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
Datasheet download
References (0)
ab204202 has not yet been referenced specifically in any publications.