Recombinant Human ICA 512/PTPRN protein (ab42590)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Tags: GST tag N-Terminus
- Suitable for: Phosphatase Activity
Description
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Product name
Recombinant Human ICA 512/PTPRN protein -
Purity
> 95 % SDS-PAGE. -
Expression system
Escherichia coli -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Predicted molecular weight
59 kDa including tags -
Amino acids
693 to 979 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab42590 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Phosphatase Activity
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Form
Liquid -
Additional notes
This protein may be useful for the study of regulation, and to dephosphorylate target substrates. It seems to lack intrinic enzyme activity.
Previously labelled as PTPIA2 / PTPRN.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.307% Glutathione, 0.0154% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.395% Tris HCl, 0.05% Tween, 0.0584% EDTA, 50% Glycerol (glycerin, glycerine), 0.435% Sodium chloride
General Info
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Alternative names
- CA 512
- FLJ16131
- IA 2
see all -
Function
Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2. -
Tissue specificity
Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary. -
Sequence similarities
Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
Contains 1 tyrosine-protein phosphatase domain. -
Post-translational
modificationsAppears to undergo multiple proteolytic cleavage at consecutive basic residues. -
Cellular localization
Membrane. Neuroendocrine secretory granules. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab42590 has not yet been referenced specifically in any publications.