Recombinant Human PDGFR alpha protein (ab109932)
Key features and details
- Expression system: Escherichia coli
- Purity: > 85% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant Human PDGFR alpha protein
See all PDGFR alpha proteins and peptides -
Purity
> 85 % SDS-PAGE.
ab109932 is purified using conventional chromatography techniques. -
Expression system
Escherichia coli -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MGSSHHHHHHSSGLVPRGSHAHTGLYTCYYNHTQTEENELEGRHIYIYVP DPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLHNSEGVVPASY DSRQGFNGTFMQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYPMS EEESSDVEIRNEENNSGLFVTVLEVSSASATVGPYICEATVKGKKFQTIP FNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNNEVVDLQWTYPGE VKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATREVKEM KKVTISVHEKGFIEIKPTFSQLEAVNLHEVKHFVVEVRAYPPPRISWLKN NLTLIENLTEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIVAQNEDAV KSYTFELLTQVPSSILDLVDDHHGSTGGQTVRCTAEGTPLPDIEWMICKD IKKCNNETSWTILANNVSNIITEIHSRDRSTVEGRVTFAKVEETIAVRCL AKNLLGAENRELKLVAPTLRSE -
Predicted molecular weight
58 kDa including tags -
Amino acids
24 to 524 -
Tags
His tag N-Terminus
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab109932 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride
General Info
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Alternative names
- Alpha-type platelet-derived growth factor receptor
- CD140 antigen-like family member A
- CD140a
see all -
Function
Receptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity. -
Tissue specificity
Expressed in primary and metastatic colon tumors and in normal colon tissue. Tumors may express a different isoform to that found in normal tissue. -
Involvement in disease
Note=A chromosomal aberration involving PDGFRA is found in some cases of hypereosinophilic syndrome. Interstitial chromosomal deletion del(4)(q12q12) causes the fusion of FIP1L1 and PDGFRA (FIP1L1-PDGFRA). -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
Cellular localization
Membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human PDGFR alpha protein (ab109932)15% SDS-PAGE showing ab109932 at approximately 58.4 kDa (3µg).
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab109932 has not yet been referenced specifically in any publications.