Recombinant mouse NRP2 protein (His tag) (ab277019)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE, Functional Studies
Description
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Product name
Recombinant mouse NRP2 protein (His tag)
See all NRP2 proteins and peptides -
Biological activity
Measured by its ability to bind rat Fc-VEGFC in functional ELISA.
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Purity
> 95 % SDS-PAGE. -
Endotoxin level
< 1.000 Eu/µg -
Expression system
HEK 293 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Mouse -
Sequence
MDMFPLTWVF LALYFSGHEV RSQQDPPCGG RLNSKDAGYI TSPGYPQDYP SHQNCEWIVY APEPNQKIVL NFNPHFEIEK HDCKYDFIEI RDGDSESADL LGKHCGNIAP PTIISSGSVL YIKFTSDYAR QGAGFSLRYE IFKTGSEDCS KNFTSPNGTI ESPGFPEKYP HNLDCTFTIL AKPRMEIILQ FLTFDLEHDP LQVGEGDCKY DWLDIWDGIP HVGPLIGKYC GTKTPSKLRS STGILSLTFH TDMAVAKDGF SARYYLIHQE PPENFQCNVP LGMESGRIAN EQISASSTFS DGRWTPQQSR LHGDDNGWTP NLDSNKEYLQ VDLRFLTMLT AIATQGAISR ETQKGYYVKS YKLEVSTNGE DWMVYRHGKN HKIFQANNDA TEVVLNKLHM PLLTRFIRIR PQTWHLGIAL RLELFGCRVT DAPCSNMLGM LSGLIADTQI SASSTREYLW SPSAARLVSS RSGWFPRNPQ AQPGEEWLQV DLGTPKTVKG VIIQGARGGD SITAVEARAF VRKFKVSYSL NGKDWEYIQD PRTQQTKLFE GNMHYDTPDI RRFDPVPAQY VRVYPERWSP AGIGMRLEVL GCDWTDSKPT VETLGPTVKS EETTTPYPMD EDATECGENC SFEDDKDLQL PSGFNCNFDF PEETCGWVYD HAKWLRSTWI SSANPNDRTF PDDKNFLKLQ SDGRREGQYG RLISPPVHLP RSPVCMEFQY QAMGGHGVAL QVVREASQES KLLWVIREDQ GSEWKHGRII LPSYDMEYQI VFEGVIGKGR SGEISIDDIR ISTDVPLENC MEPISAFAGE DFKVDIPETH GGEGYEDEID DEYEGDWSNS SSSTSGAGDP SSGKEKSWLY TLDP -
Predicted molecular weight
97 kDa including tags -
Molecular weight information
The recombinant mouse NRP2 consists of 855 amino acids and predicts a molecular mass of 96.5 kDa. -
Amino acids
1 to 864 -
Tags
His tag C-Terminus -
Additional sequence information
Predicted N-terminus: Arg 21.
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Specifications
Our Abpromise guarantee covers the use of ab277019 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
Functional Studies
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBSThis product is an active protein and may elicit a biological response in vivo, handle with caution.
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ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
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Alternative names
- MGC126574
- Neuropilin 2
- Neuropilin-2
see all -
Function
High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. -
Sequence similarities
Belongs to the neuropilin family.
Contains 2 CUB domains.
Contains 2 F5/8 type C domains.
Contains 1 MAM domain. -
Domain
The tandem CUB domains mediate binding to semaphorin, while the tandem F5/8 domains are responsible for heparin and VEGF binding. -
Cellular localization
Membrane. - Information by UniProt
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab277019 has not yet been referenced specifically in any publications.