Recombinant mouse PD-L1 protein (Fc Chimera) (ab216192)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 90% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant mouse PD-L1 protein (Fc Chimera)
See all PD-L1 proteins and peptides -
Purity
> 90 % SDS-PAGE. -
Expression system
HEK 293 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Mouse -
Sequence
FT ITAPKDLYVV EYGSNVTMEC RFPVERELDL LALVVYWEKE DEQVIQFVAG EEDLKPQHSN FRGRASLPKD QLLKGNAALQ ITDVKLQDAG VYCCIISYGG ADYKRITLKV NAPYRKINQR ISVDPATSEH ELICQAEGYP EAEVIWTNSD HQPVSGKRSV TTSRTEGMLL NVTSSLRVNA TANDVFYCTF WRSQPGQNHT AELIIPELPA THPPQNRT -
Predicted molecular weight
52 kDa including tags -
Amino acids
19 to 238 -
Additional sequence information
Extracellular domain fused at the C-terminus to the Fc portion of mouse IgG2a.
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Specifications
Our Abpromise guarantee covers the use of ab216192 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Additional notes
Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.
Storing diluted protein is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%).
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 20% Glycerol (glycerin, glycerine), 0.02% Potassium chloride, 0.64% Sodium chloride, Phosphate BufferThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- B7 H
- B7 H1
- B7 homolog 1
see all -
Function
Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. -
Tissue specificity
Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes. -
Sequence similarities
Belongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Cell membrane and Endomembrane system. - Information by UniProt
Images
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Size Exclusion Chromatography - Recombinant mouse PD-L1 protein (Fc Chimera) (ab216192)
Gel Filtration Curve.
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SDS-PAGE - Recombinant mouse PD-L1 protein (Fc Chimera) (ab216192)4-20% SDS-PAGE Coomassie staining:
3 µg ab216192.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab216192 has not yet been referenced specifically in any publications.