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Rabbit polyclonal to Profilin 2
Predicted to work with:
Recombinant protein fragment corresponding to a region within amino acids 1 and 120 of Human Profilin 2 (NP_002619).
293T, A431, H1299, HeLaS3, HepG2, MOLT4 and Raji cell lysates
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol, 1.21% Tris, 0.75% Glycine
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 15 kDa.
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
Belongs to the profilin family.
Cytoplasm > cytoskeleton.
Information by UniProt
PFN 2 antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"