• Product name

    Anti-Prokineticin 2/PK2 antibody
    See all Prokineticin 2/PK2 primary antibodies
  • Description

    Rabbit polyclonal to Prokineticin 2/PK2
  • Host species

  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
    Predicted to work with: Macaque monkey, Gorilla
  • Immunogen

    Synthetic peptide corresponding to Human Prokineticin 2/PK2 aa 100 to the C-terminus conjugated to keyhole limpet haemocyanin.
    (Peptide available as ab123828)

  • Positive control

    • This antibody gave a positive signal in the following tissue lysates: Human Testis; Human Small Intestine; Mouse Testis; Rat Testis.
  • General notes

     This product was previously labelled as Prokineticin 2




Our Abpromise guarantee covers the use of ab87360 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 21 kDa (predicted molecular weight: 14 kDa).


  • Function

    May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle.
  • Tissue specificity

    Expressed in the testis and, at low levels, in the small intestine.
  • Involvement in disease

    Defects in PROK2 are the cause of Kallmann syndrome type 4 (KAL4) [MIM:610628]; also known as hypogonadotropic hypogonadism and anosmia. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin-releasing hormone-synthesizing neurons. KAL4 patients have variable degrees of olfactory and reproductive dysfunction, but do not show any of the occasional clinical anomalies reported in Kallmann syndrome such as renal agenesis, cleft lip/palate, selective tooth agenesis, and bimanual synkinesis.
  • Sequence similarities

    Belongs to the AVIT (prokineticin) family.
  • Cellular localization

  • Information by UniProt
  • Database links

  • Alternative names

    • BV8 antibody
    • Bv8 homolog antibody
    • MIT1 antibody
    • PK2 antibody
    • PROK2 antibody
    • PROK2_HUMAN antibody
    • Prokineticin-2 antibody
    • Protein Bv8 homolog antibody
    see all


  • All lanes : Anti-Prokineticin 2/PK2 antibody (ab87360) at 1 µg/ml

    Lane 1 : Human testis tissue lysate - total protein (ab30257)
    Lane 2 : Human small intestine tissue lysate - total protein (ab29276)
    Lane 3 : Testis (Mouse) Tissue Lysate
    Lane 4 : Testis (Rat) Tissue Lysate

    Lysates/proteins at 10 µg per lane.

    All lanes : Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution

    Developed using the ECL technique.

    Performed under reducing conditions.

    Predicted band size: 14 kDa
    Observed band size: 21 kDa
    why is the actual band size different from the predicted?
    Additional bands at: 115 kDa. We are unsure as to the identity of these extra bands.

    Exposure time: 20 minutes


This product has been referenced in:

  • Zhang Y  et al. MicroRNA-374a Governs Aggressive Cell Behaviors of Glioma by Targeting Prokineticin 2. Technol Cancer Res Treat 18:1533033818821401 (2019). Read more (PubMed: 30803356) »
See 1 Publication for this product

Customer reviews and Q&As


L'anticorps anti-Prokineticin 2 ab87360 a été caractérisé en Western Blot selon le protocole suivant:

Conditions dénaturantes et réductrices
10µg de lysat par puit
Saturation de la membrane de nitrocellulose avec 5% de BSA (pendant une heure)
Incubation du primaire à 4ºC sur la nuit, dilué à 1 µg/ml dans la solution saturante

Read More

For licensing inquiries, please contact partnerships@abcam.com

Sign up