Anti-Prol1 antibody (ab119999)
Key features and details
- Goat polyclonal to Prol1
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-Prol1 antibody
See all Prol1 primary antibodies -
Description
Goat polyclonal to Prol1 -
Host species
Goat -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Synthetic peptide corresponding to Mouse Prol1 aa 1-100 (internal sequence) (Cysteine residue).
Database link: NP_032670.2 -
Positive control
- IHC-P: Mouse submandibular salivery gland.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab119999 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab119999 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 3 µg/ml.
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Notes |
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IHC-P
Use a concentration of 3 µg/ml. |
Target
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Relevance
Opiorphin is an endogenous inhibitor of neprilysin and aminopeptidase N. Inhibits the breakdown of substance P, Mca-BK2 and Met-enkephalin by neprilysin in vitro with IC50 values of 29 µM, 33 µM and 33 µM respectively. Inhibits the breakdown of Ala-pNA by aminopeptidase N in vitro with an IC50 of 65 µM. Has a potent analgesic effect when administered to rats by intravenous injection. -
Cellular localization
Secreted -
Database links
- Entrez Gene: 17830 Mouse
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Alternative names
- Basic proline rich lacrimal protein antibody
- Basic proline rich protein antibody
- BPLP antibody
see all
Images
Datasheets and documents
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Datasheet download
References (3)
ab119999 has been referenced in 3 publications.
- Kameyama A et al. Bmi-1 regulates mucin levels and mucin O-glycosylation in the submandibular gland of mice. PLoS One 16:e0245607 (2021). PubMed: 33465144
- Praktiknjo SD et al. Tracing tumorigenesis in a solid tumor model at single-cell resolution. Nat Commun 11:991 (2020). PubMed: 32080185
- Kameyama A et al. A rapid separation and characterization of mucins from mouse submandibular glands by supported molecular matrix electrophoresis. Biochim Biophys Acta N/A:N/A (2018). WB . PubMed: 29753090