Key features and details
- Mouse monoclonal [B6.2 + PRLR742] to Prolactin Receptor/PRL-R
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-Prolactin Receptor/PRL-R antibody [B6.2 + PRLR742]
See all Prolactin Receptor/PRL-R primary antibodies
DescriptionMouse monoclonal [B6.2 + PRLR742] to Prolactin Receptor/PRL-R
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
- IHC-P: Human testicular carcinoma tissue.
Please note that this antibody is an oligoclonal antibody. It is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies have not only the specificity and batch-to-batch consistency of a monoclonal antibody, but also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen.
Previously labelled as Prolactin Receptor.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.05% BSA
Concentration information loading...
PurityProtein G purified
Purification notesab199015 was purified from Bioreactor Concentrate.
Clone numberB6.2 + PRLR742
Light chain typekappa
Our Abpromise guarantee covers the use of ab199015 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
30 minutes at RT.
FunctionThis is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.
Tissue specificityExpressed in breast, placenta, kidney, liver and pancreas.
Sequence similaritiesBelongs to the type I cytokine receptor family. Type 1 subfamily.
Contains 2 fibronectin type-III domains.
DomainThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation.
Cellular localizationSecreted and Membrane.
- Information by UniProt
- AI987712 antibody
- CLONE SPM213 antibody
- CPRLP antibody
ab199015 has not yet been referenced specifically in any publications.