Anti-Prominin 2 antibody (ab74997)
Key features and details
- Rabbit polyclonal to Prominin 2
- Suitable for: ELISA, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-Prominin 2 antibody
See all Prominin 2 primary antibodies -
Description
Rabbit polyclonal to Prominin 2 -
Host species
Rabbit -
Tested applications
Suitable for: ELISA, WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide corresponding to Human Prominin 2 aa 315-338.
Sequence:RTLELGADFSQVPSVDHVLHQLKG
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.02% Sodium azide
Antibody stabilization buffer -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Conjugation kits
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab74997 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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Notes |
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ELISA
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
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Tissue specificity
Present in saliva within small membrane particles (at protein level). Expressed in kidney, prostate, trachea, esophagus, salivary gland, thyroid gland, mammary gland adrenal gland, placenta, stomach, spinal cord and liver. In submucosal tumor, expressed in spindle-shaped or stellate stromal cells. Expressed in prostate cancer cell lines. -
Sequence similarities
Belongs to the prominin family. -
Post-translational
modificationsGlycosylated. -
Cellular localization
Apical cell membrane. Basolateral cell membrane. Cell projection > microvillus membrane. Cell projection > cilium membrane. Colocalizes with PROM1. Associates with membrane in a cholesterol-dependent manner. Localizes to the apical and basolateral membranes of epithelial cells. - Information by UniProt
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Database links
- Entrez Gene: 150696 Human
- Entrez Gene: 192212 Mouse
- Entrez Gene: 192211 Rat
- SwissProt: Q8N271 Human
- SwissProt: Q3UUY6 Mouse
- SwissProt: Q8CJ52 Rat
- Unigene: 469313 Human
- Unigene: 34171 Mouse
see all -
Alternative names
- hPROML2 antibody
- MGC138714 antibody
- OTTHUMP00000160939 antibody
see all
Protocols
Datasheets and documents
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Datasheet download
References (1)
ab74997 has been referenced in 1 publication.
- Pereira MF et al. Effects of the oestrogen receptor antagonist Fulvestrant on expression of genes that affect organization of the epididymal epithelium. Andrology 2:559-71 (2014). PubMed: 24782439