Key features and details
- Mouse monoclonal [10-18] to Properdin/PFC
- Suitable for: ELISA, IHC-Fr, Functional Studies
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-Properdin/PFC antibody [10-18]
See all Properdin/PFC primary antibodies
DescriptionMouse monoclonal [10-18] to Properdin/PFC
Tested applicationsSuitable for: ELISA, IHC-Fr, Functional Studiesmore details
Species reactivityReacts with: Human
Full length native protein (purified) corresponding to Human Properdin/PFC.
- Histology positive control tissue: Kidney from post streptococcal glomerulonephritis patients.
This product was previously labelled as Properdin
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 8.20
Preservative: 0.1% Sodium azide
Constituent: 99% Borate buffered saline
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab58984 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
FuncS: Use at an assay dependent dilution.
Note: This antibody inhibits the function of Properdin. Removal of sodium azide is recommended prior to use in functional assays
IHC-Fr: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionA positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes.
Involvement in diseaseDefects in CFP are the cause of properdin deficiency (PFD) [MIM:312060]. PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III).
Sequence similaritiesContains 6 TSP type-1 domains.
- Information by UniProt
- BFD antibody
- CFP antibody
- Complement factor P antibody
ab58984 has not yet been referenced specifically in any publications.