Overview

  • Product name

    Anti-Prostaglandin D Synthase (hematopoietic) antibody
    See all Prostaglandin D Synthase (hematopoietic) primary antibodies
  • Description

    Rabbit polyclonal to Prostaglandin D Synthase (hematopoietic)
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity

    Reacts with: Rat
  • Immunogen

    Full length native protein (purified) (Rat).

  • General notes


    This antibody is specific for hematopoietic form PGD Synthase, and does not cross react with brain form of PGD Synthase.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer

    Preservative: 0.05% Sodium azide
    Constituent: Whole serum
  • Purity

    Whole antiserum
  • Primary antibody notes

    This antibody is specific for hematopoietic form PGD Synthase, and does not cross react with brain form of PGD Synthase.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab23724 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/800. Predicted molecular weight: 22 kDa.
ELISA 1/800.
IHC-P Use at an assay dependent concentration.

Target

  • Function

    Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.
  • Tissue specificity

    Expressed in a number of megakaryocytic cell lines but not in platelets. Highly expressed in adipose tissue, macrophages and placenta. Also expressed at lower levels in lung, heart, lymph nodes, appendix, bone marrow and fetal liver.
  • Sequence similarities

    Belongs to the GST superfamily. Sigma family.
    Contains 1 GST C-terminal domain.
    Contains 1 GST N-terminal domain.
  • Developmental stage

    Highest levels in immature megakaryocytic cells. Disappears after final differentiation to platelets.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cerebrin 28 antibody
    • Glutathione dependent PGD synthetase antibody
    • Glutathione S-transferase antibody
    • Glutathione-dependent PGD synthase antibody
    • Glutathione-requiring prostaglandin D synthase antibody
    • GST class-sigma antibody
    • H PGDS antibody
    • H-PGDS antibody
    • Haematopoietic prostaglandin D synthase antibody
    • Haematopoietic prostaglandin D2 synthase antibody
    • Hematopoietic prostaglandin D synthase antibody
    • Hpgds antibody
    • HPGDS_HUMAN antibody
    • Prostaglandin D synthase antibody
    • Prostaglandin D2 synthase hematopoietic antibody
    • Prostaglandin H2 D isomerase antibody
    • Prostaglandin-H2 D-isomerase antibody
    • PTGDS2 antibody
    see all

References

ab23724 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Western blot
Sample
Rat Tissue lysate - other (Prefrontal Cortex)
Gel Running Conditions
Reduced Denaturing
Loading amount
15 µg
Specification
Prefrontal Cortex
Blocking step
BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C

Abcam user community

Verified customer

Submitted Nov 19 2015

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up