• Product name

    Anti-Prostaglandin D Synthase (hematopoietic) antibody
    See all Prostaglandin D Synthase (hematopoietic) primary antibodies
  • Description

    Rabbit polyclonal to Prostaglandin D Synthase (hematopoietic)
  • Host species

  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 36 - 85 (QADWPEIKST LPFGKIPILE VDGLTLHQSL AIARYLTKNT DLAGNTEMEQ) of Human Prostaglandin D Synthase (hematopoietic) (NP_055300).

  • Positive control

    • Human fetal spleen lysate.


  • Form

  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: PBS, 2% Sucrose
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

  • Isotype

  • Research areas


Our Abpromise guarantee covers the use of ab89709 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 4 - 8 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 23 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • Function

    Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.
  • Tissue specificity

    Expressed in a number of megakaryocytic cell lines but not in platelets. Highly expressed in adipose tissue, macrophages and placenta. Also expressed at lower levels in lung, heart, lymph nodes, appendix, bone marrow and fetal liver.
  • Sequence similarities

    Belongs to the GST superfamily. Sigma family.
    Contains 1 GST C-terminal domain.
    Contains 1 GST N-terminal domain.
  • Developmental stage

    Highest levels in immature megakaryocytic cells. Disappears after final differentiation to platelets.
  • Cellular localization

  • Information by UniProt
  • Database links

  • Alternative names

    • Cerebrin 28 antibody
    • Glutathione dependent PGD synthetase antibody
    • Glutathione S-transferase antibody
    • Glutathione-dependent PGD synthase antibody
    • Glutathione-requiring prostaglandin D synthase antibody
    • GST class-sigma antibody
    • H PGDS antibody
    • H-PGDS antibody
    • Haematopoietic prostaglandin D synthase antibody
    • Haematopoietic prostaglandin D2 synthase antibody
    • Hematopoietic prostaglandin D synthase antibody
    • Hpgds antibody
    • HPGDS_HUMAN antibody
    • Prostaglandin D synthase antibody
    • Prostaglandin D2 synthase hematopoietic antibody
    • Prostaglandin H2 D isomerase antibody
    • Prostaglandin-H2 D-isomerase antibody
    • PTGDS2 antibody
    see all


  • Anti-Prostaglandin D Synthase (hematopoietic) antibody (ab89709) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal spleen lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size: 23 kDa

    Gel concentration: 12%
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung tissue labelling Prostaglandin D Synthase with ab89709 at 4-8µg/ml.


This product has been referenced in:

  • Feng X  et al. Eosinophil production of prostaglandin D2 in patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol 138:1089-1097.e3 (2016). Read more (PubMed: 27423494) »
See 1 Publication for this product

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