Key features and details
- Rabbit polyclonal to Prostaglandin D2 Receptor - Cytoplasmic domain
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Prostaglandin D2 Receptor antibody - Cytoplasmic domain
See all Prostaglandin D2 Receptor primary antibodies
DescriptionRabbit polyclonal to Prostaglandin D2 Receptor - Cytoplasmic domain
SpecificityBLAST analysis of the peptide immunogen showed no homology with other Human proteins.
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Monkey, Gorilla
A 19 amino acid synthetic peptide from within the 3rd cytoplasmic domain of Human Prostaglandin D2 Receptor (Q13258).
- Human small intestine tissue.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.1% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab140938 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
FunctionReceptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate.
Tissue specificityExpressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes.
Involvement in diseaseGenetic variations in PTGDR are associated with susceptibility to asthma-related traits type 1 (ASRT1) [MIM:607277]. Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing and dyspnea.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
- AS 1 antibody
- AS1 antibody
- ASRT 1 antibody
ab140938 has not yet been referenced specifically in any publications.