Anti-Prostaglandin E Receptor EP2/PTGER2 antibody (ab124419)
Key features and details
- Rabbit polyclonal to Prostaglandin E Receptor EP2/PTGER2
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-Prostaglandin E Receptor EP2/PTGER2 antibody
See all Prostaglandin E Receptor EP2/PTGER2 primary antibodies -
Description
Rabbit polyclonal to Prostaglandin E Receptor EP2/PTGER2 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat -
Immunogen
Synthetic peptide corresponding to Human Prostaglandin E Receptor EP2/PTGER2 (C terminal).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
(without Mg2+, Ca2+) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab124419 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Predicted molecular weight: 40 kDa.
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IHC-P |
Use a concentration of 5 µg/ml.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 40 kDa. |
IHC-P
Use a concentration of 5 µg/ml. |
Target
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Function
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle. -
Tissue specificity
Placenta and lung. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 5732 Human
- Entrez Gene: 19217 Mouse
- Entrez Gene: 100360765 Rat
- Entrez Gene: 81752 Rat
- Omim: 176804 Human
- SwissProt: P43116 Human
- SwissProt: Q62053 Mouse
- SwissProt: Q62928 Rat
see all -
Alternative names
- EP2 antibody
- PE2R2_HUMAN antibody
- PGE receptor EP2 subtype antibody
see all
Images
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All lanes : Anti-Prostaglandin E Receptor EP2/PTGER2 antibody (ab124419) at 1/500 dilution
Lane 1 : Mouse liver cell extract
Lane 2 : Mouse liver cell extract with synthesized peptide
Predicted band size: 40 kDa -
Staining of Prostaglandin E Receptor EP2/PTGER2 in Paraffin-embedded Human Uterus, Myometrium tissue by Immunohistochemistry using ab124419 at a concentration of 5 µg/ml.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab124419 has been referenced in 2 publications.
- Mochocki M et al. Expression of prostaglandin E2 prostanoid receptor EP2 and interleukin-1ß in laryngeal carcinoma - preliminary study. Contemp Oncol (Pozn) 19:113-9 (2015). IHC-P ; Human . PubMed: 26034388
- Kaul V et al. Prostanoid receptor 2 signaling protects T helper 2 cells from BALB/c mice against activation-induced cell death. J Biol Chem 287:25434-9 (2012). WB ; Mouse . PubMed: 22654101