Anti-Prostaglandin E Synthase/MPGES-1 antibody (ab62050)
Key features and details
- Rabbit polyclonal to Prostaglandin E Synthase/MPGES-1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Prostaglandin E Synthase/MPGES-1 antibody
See all Prostaglandin E Synthase/MPGES-1 primary antibodies -
Description
Rabbit polyclonal to Prostaglandin E Synthase/MPGES-1 -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species IHC-P Human
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Immunogen
Synthetic peptide corresponding to Human Prostaglandin E Synthase/MPGES-1 (N terminal) conjugated to keyhole limpet haemocyanin.
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General notes
Previously labelled as Prostaglandin E Synthase
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab62050 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| Application | Species |
|---|---|
| IHC-P |
Human
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| All applications |
Rat
Rabbit
Chicken
Cow
Dog
Pig
Xenopus laevis
Monkey
Zebrafish
|
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | (1) |
Use a concentration of 10 µg/ml.
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| Notes |
|---|
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IHC-P
Use a concentration of 10 µg/ml. |
Target
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Function
Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). -
Sequence similarities
Belongs to the MAPEG family. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 417193 Chicken
- Entrez Gene: 282019 Cow
- Entrez Gene: 9536 Human
- Entrez Gene: 59103 Rat
- Entrez Gene: 544666 Zebrafish
- Omim: 605172 Human
- SwissProt: O14684 Human
- Unigene: 146688 Human
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Alternative names
- Glutathione S transferase 1 like 1 antibody
- MGC10317 antibody
- MGST IV antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Prostaglandin E Synthase/MPGES-1 antibody (ab62050)This image is courtesy of an anonymous Abreview
ab62050 staining Prostaglandin E Synthase/MPGES-1 in Mouse testis tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with paraformaldehyde, permeabilized with Triton-X and blocked with 10% serum for 30 minutes at 24°C; antigen retrieval was by heat mediation in a citrate buffer. Samples were incubated with primary antibody (1/50) for 20 hours at 4°C. ab150075, a donkey anti-rabbit Alexa Fluor® 647- (1/200) was used as the secondary antibody.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Prostaglandin E Synthase/MPGES-1 antibody (ab62050)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue, staining Prostaglandin E Synthase/MPGES-1 with ab62050 at 10 µg/ml.
Datasheets and documents
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SDS download
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Datasheet download
References (7)
ab62050 has been referenced in 7 publications.
- Akthar I et al. In vitro and in vivo impairment of embryo implantation by commonly used fungicide Mancozeb. Biochem Biophys Res Commun 527:42-48 (2020). PubMed: 32446389
- Chen Z et al. CRISPR/Cas9-based liver-derived reporter cells for screening of mPGES-1 inhibitors. J Enzyme Inhib Med Chem 34:799-807 (2019). PubMed: 30879343
- Berisha B et al. Prostaglandins in Superovulation Induced Bovine Follicles During the Preovulatory Period and Early Corpus Luteum. Front Endocrinol (Lausanne) 10:467 (2019). PubMed: 31354631
- Berisha B et al. Changes in the expression of prostaglandin family members in bovine corpus luteum during the estrous cycle and pregnancy. Mol Reprod Dev 85:622-634 (2018). PubMed: 29877057
- Maseda D et al. mPGES-1-Mediated Production of PGE2 and EP4 Receptor Sensing Regulate T Cell Colonic Inflammation. Front Immunol 9:2954 (2018). PubMed: 30619314
- Uchida K et al. Transforming growth factor activating kinase 1 regulates extracellular matrix degrading enzymes and pain-related molecule expression following tumor necrosis factor-a stimulation of synovial cells: an in vitro study. BMC Musculoskelet Disord 18:283 (2017). PubMed: 28668088
- Shi X et al. The involvement and possible mechanism of NR4A1 in chondrocyte apoptosis during osteoarthritis. Am J Transl Res 9:746-754 (2017). PubMed: 28337303