Key features and details
- Rabbit polyclonal to Prostate Secretory Protein/PSP
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-Prostate Secretory Protein/PSP antibody
See all Prostate Secretory Protein/PSP primary antibodies
DescriptionRabbit polyclonal to Prostate Secretory Protein/PSP
Specificityab196754 detects endogenous level of total MSMB protein.
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Recombinant full length protein within Human Prostate Secretory Protein/PSP. The exact sequence is proprietary.
Database link: P08118
- Mouse liver, kidney and skeletal muscle tissue extracts; rat kidney, Human esophagal cancer and mouse lung tissues.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
PBS is without Mg2+ and Ca2+.
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab196754 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/100.|
|WB||1/500 - 1/2000. Predicted molecular weight: 13 kDa.|
Tissue specificityStrongly expressed in prostate, liver, kidney, breast and penis. Also expressed in pancreas, esophagus, stomach, deodenum, colon, trachea, lung, salivary glands and fallopian tube. PSP94 is expressed in lung and breast, whereas PSP57 is found in kidney and bladder.
Involvement in diseaseDefects in MSMB are the cause of susceptibility to prostate cancer hereditary type 13 (HPC13) [MIM:611928]. It is a condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma.
Sequence similaritiesBelongs to the beta-microseminoprotein family.
Cellular localizationSecreted. Sperm surface.
- Information by UniProt
- Beta microseminoprotein [Precursor] antibody
- Beta-microseminoprotein antibody
- HPC 13 antibody
All lanes : Anti-Prostate Secretory Protein/PSP antibody (ab196754) at 1/500 dilution
Lane 1 : Mouse liver extract
Lane 2 : Mouse kidney extract
Lane 3 : Mouse skeletal muscle extract
Predicted band size: 13 kDa
Immunohistochemical analysis of paraffin-embedded rat kidney tissue labeling Prostate Secretory Protein/PSP with ab196754 at a 1/100 dilution (400x lens).
Immunohistochemical analysis of paraffin-embedded Human esophagal cancer tissue labeling Prostate Secretory Protein/PSP with ab196754 at a 1/100 dilution (400x lens).
Immunohistochemical analysis of paraffin-embedded mouse lung tissue labeling Prostate Secretory Protein/PSP with ab196754 at a 1/100 dilution (400x lens).
ab196754 has not yet been referenced specifically in any publications.