Overview

  • Product name

    Anti-Prostate Secretory Protein/PSP antibody
    See all Prostate Secretory Protein/PSP primary antibodies
  • Description

    Rabbit polyclonal to Prostate Secretory Protein/PSP
  • Host species

    Rabbit
  • Specificity

    ab196754 detects endogenous level of total MSMB protein.
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length protein within Human Prostate Secretory Protein/PSP. The exact sequence is proprietary.
    Database link: P08118

  • Positive control

    • Mouse liver, kidney and skeletal muscle tissue extracts; rat kidney, Human esophagal cancer and mouse lung tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab196754 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
WB 1/500 - 1/2000. Predicted molecular weight: 13 kDa.

Target

  • Tissue specificity

    Strongly expressed in prostate, liver, kidney, breast and penis. Also expressed in pancreas, esophagus, stomach, deodenum, colon, trachea, lung, salivary glands and fallopian tube. PSP94 is expressed in lung and breast, whereas PSP57 is found in kidney and bladder.
  • Involvement in disease

    Defects in MSMB are the cause of susceptibility to prostate cancer hereditary type 13 (HPC13) [MIM:611928]. It is a condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma.
  • Sequence similarities

    Belongs to the beta-microseminoprotein family.
  • Cellular localization

    Secreted. Sperm surface.
  • Information by UniProt
  • Database links

  • Alternative names

    • Beta microseminoprotein [Precursor] antibody
    • Beta-microseminoprotein antibody
    • HPC 13 antibody
    • HPC13 antibody
    • IGBF antibody
    • Immunoglobulin binding factor antibody
    • Immunoglobulin-binding factor antibody
    • microseminoprotein beta antibody
    • Msmb antibody
    • MSMB_HUMAN antibody
    • MSP antibody
    • MSPB antibody
    • PN 44 antibody
    • PN44 antibody
    • Prostate secreted seminal plasma protein antibody
    • Prostate secretory protein of 94 amino acids antibody
    • Prostate secretory protein PSP94 antibody
    • PRPS antibody
    • PRSP antibody
    • PSP 57 antibody
    • PSP antibody
    • PSP-94 antibody
    • PSP57 antibody
    • PSP94 antibody
    • Seminal plasma beta inhibin antibody
    • Seminal plasma beta-inhibin antibody
    see all

Images

  • All lanes : Anti-Prostate Secretory Protein/PSP antibody (ab196754) at 1/500 dilution

    Lane 1 : Mouse liver extract
    Lane 2 : Mouse kidney extract
    Lane 3 : Mouse skeletal muscle extract

    Predicted band size: 13 kDa

  • Immunohistochemical analysis of paraffin-embedded rat kidney tissue labeling Prostate Secretory Protein/PSP with ab196754 at a 1/100 dilution (400x lens).

  • Immunohistochemical analysis of paraffin-embedded Human esophagal cancer tissue labeling Prostate Secretory Protein/PSP with ab196754 at a 1/100 dilution (400x lens).

  • Immunohistochemical analysis of paraffin-embedded mouse lung tissue labeling Prostate Secretory Protein/PSP with ab196754 at a 1/100 dilution (400x lens).

References

ab196754 has not yet been referenced specifically in any publications.

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