Recombinant
RabMAb

Recombinant Anti-Prostate Secretory Protein/PSP antibody [EPR7345] (ab128897)

Overview

  • Product name

    Anti-Prostate Secretory Protein/PSP antibody [EPR7345]
    See all Prostate Secretory Protein/PSP primary antibodies
  • Description

    Rabbit monoclonal [EPR7345] to Prostate Secretory Protein/PSP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IP, IHC-Pmore details
    Unsuitable for: ICC
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide to Human Prostate Secretory Protein/PSP (UniProt P08118).

  • Positive control

    • Human prostate and Human prostate cancer lysates, Human prostate tissue.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab128897 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000 - 1/50000. Detects a band of approximately 16 kDa (predicted molecular weight: 13 kDa).
IP 1/10 - 1/100.
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
  • Application notes
    Is unsuitable for ICC.
  • Target

    • Tissue specificity

      Strongly expressed in prostate, liver, kidney, breast and penis. Also expressed in pancreas, esophagus, stomach, deodenum, colon, trachea, lung, salivary glands and fallopian tube. PSP94 is expressed in lung and breast, whereas PSP57 is found in kidney and bladder.
    • Involvement in disease

      Defects in MSMB are the cause of susceptibility to prostate cancer hereditary type 13 (HPC13) [MIM:611928]. It is a condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma.
    • Sequence similarities

      Belongs to the beta-microseminoprotein family.
    • Cellular localization

      Secreted. Sperm surface.
    • Information by UniProt
    • Database links

    • Alternative names

      • Beta microseminoprotein [Precursor] antibody
      • Beta-microseminoprotein antibody
      • HPC 13 antibody
      • HPC13 antibody
      • IGBF antibody
      • Immunoglobulin binding factor antibody
      • Immunoglobulin-binding factor antibody
      • microseminoprotein beta antibody
      • Msmb antibody
      • MSMB_HUMAN antibody
      • MSP antibody
      • MSPB antibody
      • PN 44 antibody
      • PN44 antibody
      • Prostate secreted seminal plasma protein antibody
      • Prostate secretory protein of 94 amino acids antibody
      • Prostate secretory protein PSP94 antibody
      • PRPS antibody
      • PRSP antibody
      • PSP 57 antibody
      • PSP antibody
      • PSP-94 antibody
      • PSP57 antibody
      • PSP94 antibody
      • Seminal plasma beta inhibin antibody
      • Seminal plasma beta-inhibin antibody
      see all

    Images

    • All lanes : Anti-Prostate Secretory Protein/PSP antibody [EPR7345] (ab128897) at 1/10000 dilution

      Lane 1 : Human prostate lysate
      Lane 2 : Human prostate cancer lysate

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 13 kDa
      Observed band size: 16 kDa
      why is the actual band size different from the predicted?

    • ab128897, at a dilution of 1/500, staining Prostate Secretory Protein/PSP in paraffin-embedded Human Prostate tissue by Immunohistochemistry.

    References

    ab128897 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab128897.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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