Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7345] to Prostate Secretory Protein/PSP
- Suitable for: WB, IP, IHC-P
- Reacts with: Human
Product nameAnti-Prostate Secretory Protein/PSP antibody [EPR7345]
See all Prostate Secretory Protein/PSP primary antibodies
DescriptionRabbit monoclonal [EPR7345] to Prostate Secretory Protein/PSP
Tested applicationsSuitable for: WB, IP, IHC-Pmore details
Unsuitable for: ICC
Species reactivityReacts with: Human
Synthetic peptide to Human Prostate Secretory Protein/PSP (UniProt P08118).
- Human prostate and Human prostate cancer lysates, Human prostate tissue.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
Concentration information loading...
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab128897 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/10000 - 1/50000. Detects a band of approximately 16 kDa (predicted molecular weight: 13 kDa).|
|IP||1/10 - 1/100.|
|IHC-P||1/500 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
Tissue specificityStrongly expressed in prostate, liver, kidney, breast and penis. Also expressed in pancreas, esophagus, stomach, deodenum, colon, trachea, lung, salivary glands and fallopian tube. PSP94 is expressed in lung and breast, whereas PSP57 is found in kidney and bladder.
Involvement in diseaseDefects in MSMB are the cause of susceptibility to prostate cancer hereditary type 13 (HPC13) [MIM:611928]. It is a condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma.
Sequence similaritiesBelongs to the beta-microseminoprotein family.
Cellular localizationSecreted. Sperm surface.
- Information by UniProt
- Beta microseminoprotein [Precursor] antibody
- Beta-microseminoprotein antibody
- HPC 13 antibody
All lanes : Anti-Prostate Secretory Protein/PSP antibody [EPR7345] (ab128897) at 1/10000 dilution
Lane 1 : Human prostate lysate
Lane 2 : Human prostate cancer lysate
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 13 kDa
Observed band size: 16 kDa why is the actual band size different from the predicted?
ab128897, at a dilution of 1/500, staining Prostate Secretory Protein/PSP in paraffin-embedded Human Prostate tissue by Immunohistochemistry.
Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ab128897 has not yet been referenced specifically in any publications.