Anti-Prostate Specific Antigen antibody (ab9537)
Key features and details
- Rabbit polyclonal to Prostate Specific Antigen
- Suitable for: IHC-Fr, IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-Prostate Specific Antigen antibody
See all Prostate Specific Antigen primary antibodies -
Description
Rabbit polyclonal to Prostate Specific Antigen -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Fr, IHC-P, ICC/IFmore details -
Species reactivity
Reacts with: Human -
Immunogen
Full length native protein (purified) corresponding to Human Prostate Specific Antigen. Isolated from human seminal plasma.
Database link: P07288 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.3
Preservative: 0.05% Sodium azide
Constituent: 1% BSA -
Concentration information loading...
-
Purity
IgG fraction -
Clonality
Polyclonal -
Myeloma
unknown -
Isotype
IgG -
Light chain type
unknown -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab9537 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-Fr |
Use at an assay dependent concentration.
|
|
IHC-P |
1/50 - 1/150.
|
|
ICC/IF | (1) |
Use at an assay dependent concentration.
|
Notes |
---|
IHC-Fr
Use at an assay dependent concentration. |
IHC-P
1/50 - 1/150. |
ICC/IF
Use at an assay dependent concentration. |
Target
-
Function
Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. -
Sequence similarities
Belongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain. -
Cellular localization
Secreted. - Information by UniProt
-
Database links
- Entrez Gene: 354 Human
- Omim: 176820 Human
- SwissProt: P07288 Human
- Unigene: 171995 Human
-
Alternative names
- antigen, prostate-specific antibody
- APS antibody
- Gamma seminoprotein antibody
see all
Images
-
Formalin-fixed, paraffin-embeded human prostate carcinoma tissue stained for Prostate Specific Antigen using ab9537 at 1/50 dilution in immunohistochemical analysis. Antigen retrieval with citrate buffer pH 6.0.
-
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human prostate carcinoma tissue, staining Prostate Specific Antigen with ab9537. Staining was detected using DAB.
Protocols
Datasheets and documents
-
Datasheet download
References (7)
ab9537 has been referenced in 7 publications.
- Balint B et al. Left atrial microvascular endothelial dysfunction, myocardial inflammation and fibrosis after selective insular cortex ischemic stroke. Int J Cardiol 292:148-155 (2019). PubMed: 31196685
- Sanz G et al. Structurally related odorant ligands of the olfactory receptor OR51E2 differentially promote metastasis emergence and tumor growth. Oncotarget 8:4330-4341 (2017). PubMed: 28032594
- Sanz G et al. Gallein, a Gß? subunit signalling inhibitor, inhibits metastatic spread of tumour cells expressing OR51E2 and exposed to its odorant ligand. BMC Res Notes 10:541 (2017). PubMed: 29084601
- Sanz G et al. Promotion of cancer cell invasiveness and metastasis emergence caused by olfactory receptor stimulation. PLoS One 9:e85110 (2014). IHC (PFA fixed) ; Mouse . PubMed: 24416348
- Berry SM et al. Streamlining immunoassays with immiscible filtrations assisted by surface tension. Anal Chem 84:5518-23 (2012). PubMed: 22632629
- Drake RR et al. Clinical collection and protein properties of expressed prostatic secretions as a source for biomarkers of prostatic disease. J Proteomics 72:907-17 (2009). PubMed: 19457353
- Pettus JR et al. Multiple kallikrein (KLK 5, 7, 8, and 10) expression in squamous cell carcinoma of the oral cavity. Histol Histopathol 24:197-207 (2009). IHC-P ; Human . PubMed: 19085836