Anti-Proteinase Activated Receptor 3/PAR-3 antibody (ab200400)

Overview

  • Product name

    Anti-Proteinase Activated Receptor 3/PAR-3 antibody
    See all Proteinase Activated Receptor 3/PAR-3 primary antibodies
  • Description

    Rabbit polyclonal to Proteinase Activated Receptor 3/PAR-3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Proteinase Activated Receptor 3/PAR-3 (internal sequence). (NP_004092 )
    Database link: O00254

  • Positive control

    • Human prostate cancer tissue, Human colon cancer tissue
  • General notes

    Protein previously labeled as Proteinase Activated Receptor 3.

Properties

Applications

Our Abpromise guarantee covers the use of ab200400 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100.

Target

  • Function

    Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
  • Tissue specificity

    Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications

    A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • coagulation factor II (thrombin) receptor-like 2 antibody
    • Coagulation factor II receptor-like 2 antibody
    • F2RL2 antibody
    • PAR 3 antibody
    • PAR-3 antibody
    • PAR3 antibody
    • PAR3_HUMAN antibody
    • protease activated receptor 3 antibody
    • Proteinase-activated receptor 3 antibody
    • thrombin receptor like 2 antibody
    • Thrombin receptor-like 2 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue labeling Proteinase Activated Receptor 3/PAR-3 with ab200400 at 1/30 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue labeling Proteinase Activated Receptor 3/PAR-3 with ab200400 at 1/30 dilution.

References

ab200400 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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