Anti-Proteinase Activated Receptor 3/PAR-3 antibody - C-terminal (ab195797)

Overview

  • Product name

    Anti-Proteinase Activated Receptor 3/PAR-3 antibody - C-terminal
    See all Proteinase Activated Receptor 3/PAR-3 primary antibodies
  • Description

    Rabbit polyclonal to Proteinase Activated Receptor 3/PAR-3 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, ICC/IFmore details
    Unsuitable for: WB
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Monkey, Gorilla
  • Immunogen

    Synthetic peptide corresponding to Human Proteinase Activated Receptor 3/PAR-3 (C terminal). 14 amino acid peptide.
    Database link: O00254

  • Positive control

    • Human breast tissue.
  • General notes

    Protein previously labeled as Proteinase Activated Receptor 3.

Properties

Applications

Our Abpromise guarantee covers the use of ab195797 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 - 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function

      Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
    • Tissue specificity

      Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.
    • Sequence similarities

      Belongs to the G-protein coupled receptor 1 family.
    • Post-translational
      modifications

      A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
    • Cellular localization

      Cell membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • coagulation factor II (thrombin) receptor-like 2 antibody
      • Coagulation factor II receptor-like 2 antibody
      • F2RL2 antibody
      • PAR 3 antibody
      • PAR-3 antibody
      • PAR3 antibody
      • PAR3_HUMAN antibody
      • protease activated receptor 3 antibody
      • Proteinase-activated receptor 3 antibody
      • thrombin receptor like 2 antibody
      • Thrombin receptor-like 2 antibody
      see all

    Images

    • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human breast tissue labeling Proteinase Activated Receptor 3/PAR-3 with ab195797 at 10 µg/mL.

    References

    ab195797 has not yet been referenced specifically in any publications.

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