Protein and peptide research tools

Cytokines and growth factors

• Cytokines are important mediators in immune cell-cell communication, involved in cell movement, mediating inflammatory and immune responses, and regulating cell growth and differentiation.
• Given the importance of this group of proteins in cell signaling, we ensure that our recombinant proteins are tested for function in relevant cell models.
• Our extensive range includes interferons, chemokines, interleukins and various growth and inhibitory factors.

• Ubiquitin is a highly conserved 8.5 kDa protein that is abundant in all types of cells. It performs vital roles in cellular processes, including DNA damage responses, endocytosis, and mitosis. 
• ​As ubiquitin molecules are important players in many signal transduction pathways, enzymes that regulate these pathways serve as potential therapeutic targets in disease treatment.

Microbiology and virology proteins

• Recombinant, synthetic and natural proteins, including viral and bacterial antigens, are essential tools in the areas of microbiology and virology. Our broad range can be used in a variety of applications to aid research in existing research topics or current epidemics. 
• Our products include bacterial proteins, DNA and RNA virus proteins, Hepatitis proteins, HIV proteins, HSV and influenza proteins

Human immunoglobulin proteins

• Our human immunoglobulin proteins can be used in serology, biochemical assays and the investigation of autoimmune disorders.
• We provide both natural and recombinant human immunoglobulin proteins to a variety of popular targets, including IgE, IgG, IgA, IgD, and IgM.

Cell surface markers and receptors

• Cell surface receptors and markers are specialized proteins involved in cell signaling. Due to their presence in a vast array of cell types, they are important in several research fields, including cancer, neurodegeneration and immunology.
• Our high-quality markers and receptors will allow you to evaluate protein function for many popular targets. 

Blocking peptides

• ​Blocking peptides can be used as controls to evaluate the specificity of antibodies in applications like immunohistochemistry and western blot. We offer a wide range of verified blocking peptides, including custom blocking peptides for our RabMAb® range of rabbit monoclonal antibodies.
• If we do not have your desired blocking peptide, please contact Scientific Support with details of the antibody you wish to block.

• ​Matrix metalloproteinases (MMPs) form a family of zinc-containing endopeptidases, which play an important role in the degradation of extracellular matrix proteins. They can also affect many other biological activities, such as cell migration and growth.
• Regulation of MMP activity occurs at several levels, including transcriptional regulation and inhibition by specific protease inhibitors, called TIMPs.

• ​Kinases and transferases correspond to a class of enzymes that transfer functional groups from a donor molecule to an acceptor. Specifically, kinases catalyze the transfer of phosphate from ATP to hydroxyl side chains on proteins, causing changes in function. Transferases catalyze the transfer of a functional group (eg a methyl or phosphate group) from one molecule to another.

• Caspases are a family of cysteine proteases involved in development, cytokine maturation and programmed cell death. There are two subgroups according to their functions in cell death: initiator caspases (caspases 2, 8, 9, and 10) are activated through apoptosis-signaling pathways and activate effector caspases (caspases 3, 6 and 7), which carry out programmed cell death. 

• ​Signal transduction enzymes orchestrate a cascade of reactions involving numerous signal transduction pathways. Enzymes, such as tyrosine kinases, phosphatases and hydrolases, are central to cell signaling.