Overview

  • Product name

    Prothionamide, Antibiotic agent
  • Description

    Antibiotic agent
  • Biological description

    Antibiotic agent. Forms covalent adducts with NAD+. Shows activity anti-tuberculosis activity. Active in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    14222-60-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-Propylpyridine-4-carbothioamide
  • Molecular weight

    180.27
  • Molecular formula

    C9H12N2S
  • PubChem identifier

    666418
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCC1=NC=CC(=C1)C(=S)N
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Grosset JH  et al. Activity of ofloxacin against Mycobacterium leprae in the mouse. Int J Lepr Other Mycobact Dis 56:259-64 (1988). Read more (PubMed: 3045223) »
  • Shepard CC  et al. An experimental study of the antileprosy activity of a series of thioamides in the mouse. Int J Lepr Other Mycobact Dis 53:587-94 (1985). Read more (PubMed: 3910748) »
  • Peters JH  et al. Disposition of prothionamide in rats and armadillos. Int J Lepr Other Mycobact Dis 51:54-63 (1983). Read more (PubMed: 6602784) »

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