Overview

  • Product name

    Protopanaxadiol, ginsenoside metabolite
  • Description

    Ginsenoside Rb1 and Rb2 analog
  • Biological description

    Ginsenoside Rb1 (ab142646) and Rb2 (ab142656) analog. Enhances axonal and dendritic formation activity. Induces apoptosis. Shows moderate antiproliferative effects.
  • Purity

    > 98%
  • CAS Number

    7755-01-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,12-diol
  • Molecular weight

    460.73
  • Molecular formula

    C30H52O3
  • PubChem identifier

    3800204
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)O)C)C)O)C)O)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Qian M  et al. Chemical profiles and anticancer effects of saponin fractions of different polarity from the leaves of Panax notoginseng. Chin J Nat Med 12:30-7 (2014). Read more (PubMed: 24484594) »
  • Law CK  et al. Ginsenoside compound K induces apoptosis in nasopharyngeal carcinoma cells via activation of apoptosis-inducing factor. Chin Med 9:11 (2014). Read more (PubMed: 24690317) »
  • Zheng Y  et al. Antiproliferative effects of protopanaxadiol ginsenosides on human colorectal cancer cells. Biomed Rep 1:555-558 (2013). Read more (PubMed: 24648985) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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