Overview

  • Product name

    Anti-PRSS3/Mesotrypsin antibody
    See all PRSS3/Mesotrypsin primary antibodies
  • Description

    Rabbit polyclonal to PRSS3/Mesotrypsin
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Flow Cyt, WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human PRSS3/Mesotrypsin aa 20-48 (N terminal) conjugated to keyhole limpet haemocyanin.
    Database link: P35030-1

  • Positive control

    • MDA-MB231 cell line lysates; Human pancreas tissue
  • General notes

     This product was previously labelled as PRSS3

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    This antibody is purified through a protein A column, followed by peptide affinity purification.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab107430 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/10 - 1/50.
WB 1/100 - 1/500. Predicted molecular weight: 33 kDa.
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5.
  • Tissue specificity

    Expressed in pancreas and brain. Also expressed in Paneth cells, at the base of small intestinal crypts.
  • Sequence similarities

    Belongs to the peptidase S1 family.
    Contains 1 peptidase S1 domain.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • Brain trypsinogen antibody
    • Mesotrypsin antibody
    • Mesotrypsinogen antibody
    • MTG antibody
    • Pancreatic trypsinogen III antibody
    • Protease, serine, 3 antibody
    • Protease, serine, 4 (trypsin 4, brain) antibody
    • PRSS3 antibody
    • PRSS4 antibody
    • Serine protease 3 antibody
    • Serine protease 4 antibody
    • T9 antibody
    • TRY3 antibody
    • TRY3_HUMAN antibody
    • TRY4 antibody
    • Trypsin 3 antibody
    • Trypsin III antibody
    • Trypsin IV antibody
    • Trypsin-3 antibody
    • Trypsinogen 4 antibody
    • Trypsinogen 5 antibody
    • Trypsinogen IV antibody
    see all

Images

  • Anti-PRSS3/Mesotrypsin antibody (ab107430) at 1/100 dilution + MDA-MB231 cell line lysates at 35 µg

    Predicted band size: 33 kDa

  • ab107430, at a 1/50 dilution, staining PRSS3/Mesotrypsin in formalin fixed and paraffin embedded Human pancreas tissue by Immunohistochemistry. Detection utilised peroxidase conjugation of the secondary antibody and DAB staining.

  • Flow cytometric analysis of MDA-MN231 cells (right histogram) using ab107430 at 1/10 dilution compared to a negative control (left). A FITC-conjugated goat-anti rabbit was used as the secondary antibody.

References

This product has been referenced in:

See 1 Publication for this product

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