Overview

  • Product name

    Prulifloxacin, quinoline antibiotic agent
  • Description

    Broad spectrum quinoline antibiotic agent
  • Biological description

    Broad spectrum quinoline antibiotic agent. Prodrug of ulifloxacin. Shows activity against a variety of Gram-positive and -negative bacteria. Orally active
  • Purity

    > 97%
  • CAS Number

    123447-62-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    6-Fluoro-1-methyl-7-[4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]piperazin-1-yl]-4-oxo-1H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid
  • Molecular weight

    461.46
  • Molecular formula

    C21H20FN3O6S
  • PubChem identifier

    65947
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in 0.1 M NaOH
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1N2C3=CC(=C(C=C3C(=O)C(=C2S1)C(=O)O)F)N4CCN(CC4)CC5=C(OC(=O)O5)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Nandi U  et al. Correlation among the toxicity profiling (28-days repeated oral dose toxicity), toxicokinetics and tissue distribution data of ulifloxacin, the active metabolite of prulifloxacin in Wistar albino rats. Environ Toxicol Pharmacol 34:588-607 (2012). Read more (PubMed: 22885677) »
  • Roy B  et al. Development and validation of a liquid chromatography-tandem mass spectrometry method to determine ulifloxacin, the active metabolite of prulifloxacin in rat and rabbit plasma: application to toxicokinetic study. Biomed Chromatogr 25:890-901 (2011). Read more (PubMed: 21154639) »
  • Huang Y  et al. Investigation on interaction of prulifloxacin with pepsin: a spectroscopic analysis. Spectrochim Acta A Mol Biomol Spectrosc 75:1024-9 (2010). Read more (PubMed: 20045662) »

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