PSD93 peptide (ab5840)
Key features and details
- Purity: > 95% SDS-PAGE
- Suitable for: Blocking
Description
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Product name
PSD93 peptide -
Purity
> 95 % SDS-PAGE. -
Animal free
No -
Nature
Synthetic
Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab5840 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Blocking
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Form
Lyophilized -
Additional notes
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and PSD93, catalog ab2930. Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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ReconstitutionReconstitute with 0.1 ml of distilled water.
General Info
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Alternative names
- Channel associated protein of synapse 110
- Channel associated protein of synapses 110kD
- Channel-associated protein of synapse-110
see all -
Function
Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses. -
Sequence similarities
Belongs to the MAGUK family.
Contains 1 guanylate kinase-like domain.
Contains 3 PDZ (DHR) domains.
Contains 1 SH3 domain. -
Domain
An N-terminally truncated L27 domain is predicted in isoform 2 at positions 1 through 27. -
Post-translational
modificationsPalmitoylation of isoform 1 is not required for targeting to postsynaptic density. -
Cellular localization
Cell membrane. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Membrane. Cell projection, axon. Concentrated in soma and postsynaptic density of a subset of neurons. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab5840 has not yet been referenced specifically in any publications.
