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    psd93-peptide-ab5840.pdf

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Neuroscience Neurotransmission Intracellular Signaling Adapters
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PSD93 peptide (ab5840)

  • Datasheet
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Key features and details

  • Purity: > 95% SDS-PAGE
  • Suitable for: Blocking

Description

  • Product name

    PSD93 peptide
  • Purity

    > 95 % SDS-PAGE.

  • Animal free

    No
  • Nature

    Synthetic

Associated products

  • Related Products

    • Anti-PSD93 antibody (ab2930)

Specifications

Our Abpromise guarantee covers the use of ab5840 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form

    Lyophilized
  • Additional notes


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and PSD93, catalog ab2930. Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • Reconstitution
    Reconstitute with 0.1 ml of distilled water.

General Info

  • Alternative names

    • Channel associated protein of synapse 110
    • Channel associated protein of synapses 110kD
    • Channel-associated protein of synapse-110
    • Chapsyn 110
    • Chapsyn-110
    • Chapsyn110
    • Discs, large homolog 2 (Drosophila)
    • Disks large homolog 2
    • DKFZp781D1854
    • DKFZp781E0954
    • Dlg 2
    • dlg2
    • DLG2_HUMAN
    • Dlgh 2
    • Dlgh2
    • FLJ37266
    • Gm1197
    • MGC131811
    • Postsynaptic density protein PSD 93
    • Postsynaptic density protein PSD-93
    • Postsynaptic density protein PSD93
    • PSD 93
    • PSD93
    see all
  • Function

    Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.
  • Sequence similarities

    Belongs to the MAGUK family.
    Contains 1 guanylate kinase-like domain.
    Contains 3 PDZ (DHR) domains.
    Contains 1 SH3 domain.
  • Domain

    An N-terminally truncated L27 domain is predicted in isoform 2 at positions 1 through 27.
  • Post-translational
    modifications

    Palmitoylation of isoform 1 is not required for targeting to postsynaptic density.
  • Cellular localization

    Cell membrane. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Membrane. Cell projection, axon. Concentrated in soma and postsynaptic density of a subset of neurons.
  • Target information above from: UniProt accession Q15700 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab5840? Please let us know so that we can cite the reference in this datasheet.

    ab5840 has not yet been referenced specifically in any publications.

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